Metoprolol 100mg tablets

Country: United Kingdom

Language: English

Source: MHRA (Medicines & Healthcare Products Regulatory Agency)

Active ingredient:

Metoprolol tartrate

Available from:

Viatris UK Healthcare Ltd

ATC code:

C07AB02

INN (International Name):

Metoprolol tartrate

Dosage:

100mg

Pharmaceutical form:

Oral tablet

Administration route:

Oral

Class:

No Controlled Drug Status

Prescription type:

Valid as a prescribable product

Product summary:

BNF: 02040000; GTIN: 5016695390239 5016695390475

Patient Information leaflet

/THERMEDICINESAND-ETOPROLOL
Tell your doctor or pharmacist if you are taking,
have recently taken or might take any other
medicines of the following:
s
CLONIDINEFORHIGHBLOODPRESSUREORMIGRAINE 
If you are taking clonidine and metoprolol
together, do not stop taking clonidine unless
your doctor has told you to do so. If you have
to stop taking clonidine or metoprolol, your
doctor will give you careful instructions about
how to do it.
s
OTHERDRUGSFORYOURHEARTORTOREDUCEBLOOD
pressure, e.g. prazosin
s
OTHERBETABLOCKERSEGTIMOLOLFORGLAUCOMA
s
MONOAMINE OXIDASEINHIBITORSFORDEPRESSION
e.g. phenelzine
s
VERAPAMILDILTIAZEMHYDRALAZINENIFEDIPINE
(used to treat heart problems)
s
QUINIDINEAMIODARONEFORHEARTPROBLEMS
s
CIMETIDINEUSEDTOTREATHEARTBURN
s
CARDIACGLYCOSIDESEGDIGOXINUSEDTOTREAT
heart failure)
s
RIFAMPICINUSEDTOTREATTUBERCULOSIS
s
LIDOCAINEUSEDASALOCALANAESTHETICTORELIEVE
pain)
s
ERGOTAMINEUSEDTOTREATMIGRAINE
s
MEDICINESTOTREATOTHERMENTALILLNESSESSUCH
as phenothiazines)
s
ANTIRETROVIRALDRUGSEGRITONAVIR USEDTOTREAT
AIDS and some other conditions
s
DRUGSTOPREVENTMALARIA
s
MEDICINESTOTREATFUNGALINFECTIONS
s
ADRENALINEUSEDINEMERGENCYTREATMENTEG
allergic reactions)
s
INDOMETACINANDCELECOXIBUSEDTOTREAT
inflammation of the joints, gout and period
pain) medicines for the treatment of diabetes
(including insulin). Your doctor may need to
adjust your dose of these medicines.
Tell your doctor or pharmacist if you are taking,
have recently taken or might take other
medicines, including medicines obtained without
a prescription.
4AKING-ETOPROLOLWITHFOODDRINKANDALCOHOL
You should keep your alcohol intake to a
minimum while you are taking Metoprolol, as
alcohol may increase the effect of this drug.
0REGNANCYBREAST FEEDINGANDFERTILITY
)FYOUAREPREGNANTORBREAST FEEDINGTHINKYOU
may be pregnant or are planning to have a baby,
ask your doctor or pharmacist for advice before
taking this medicine.
$RIVINGANDUSINGMACHINES
Metoprolol may cause dizziness and tiredness, if
affected do not drive or operate machinery.

Summary of Product characteristics

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
Metoprolol Tartrate 100 mg Tablets
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains 100 mg of metoprolol tartrate.
Excipient(s) with known effect:
Each tablet contains 166 mg of lactose.
For the full list of excipients, see 6.1.
3
PHARMACEUTICAL FORM
Round, biconvex white tablet, engraved 4A6 with a breakline on
reverse.
4.
CLINICAL PARTICULARS
4.1.
THERAPEUTIC INDICATIONS
Metoprolol tablets are indicated for the management of hypertension,
angina
pectoris
and
cardiac
arrhythmias,
especially
supraventricular
tachyarrhythmias.
They may also be used as an adjunct in the treatment of
hyperthyroidism. In
the early treatment of acute myocardial infarction, metoprolol may be
used to
reduce infarct size and the incidence of ventricular fibrillation. By
providing
pain
relief,
the
need
for
opiate
analgesics
may
be
decreased.
When
administered to patients with acute myocardial infarction, metoprolol
has been
demonstrated
to
reduce
mortality.
Metoprolol
is
also
indicated
for
the
prevention of migraine.
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Posology
The dose must always be adjusted to the individual requirements of the
patient
but should not exceed 400mg/day. The following are guidelines:
Adults The usual dosage for the following indications is given below.
Hypertension:
The initial dosage is 100 mg per day in the morning,
which may be increased by 100 mg per day at weekly
intervals to a maximum of 400 mg per day, depending
on response. If control is not achieved with a single
daily dose, twice daily dosing should be initiated. Over
the dosage range most patients may be expected to
respond rapidly and satisfactory. Combination therapy
with a diuretic or another hypotensive agent may also be
considered
to
attain
a
further
reduction
in
blood
pressure.
Metoprolol may be administered with benefit both to
previously untreated patients with hypertension and to
those
in
whom
the
response
to
previous
therapy
is
inadequate. In the latter type of pat