Country: United Kingdom
Language: English
Source: MHRA (Medicines & Healthcare Products Regulatory Agency)
Metoprolol tartrate
The Boots Company Plc
C07AB02
Metoprolol tartrate
100mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 02040000
/THERMEDICINESAND-ETOPROLOL Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines of the following: s CLONIDINEFORHIGHBLOODPRESSUREORMIGRAINE If you are taking clonidine and metoprolol together, do not stop taking clonidine unless your doctor has told you to do so. If you have to stop taking clonidine or metoprolol, your doctor will give you careful instructions about how to do it. s OTHERDRUGSFORYOURHEARTORTOREDUCEBLOOD pressure, e.g. prazosin s OTHERBETABLOCKERSEGTIMOLOLFORGLAUCOMA s MONOAMINE OXIDASEINHIBITORSFORDEPRESSION e.g. phenelzine s VERAPAMILDILTIAZEMHYDRALAZINENIFEDIPINE (used to treat heart problems) s QUINIDINEAMIODARONEFORHEARTPROBLEMS s CIMETIDINEUSEDTOTREATHEARTBURN s CARDIACGLYCOSIDESEGDIGOXINUSEDTOTREAT heart failure) s RIFAMPICINUSEDTOTREATTUBERCULOSIS s LIDOCAINEUSEDASALOCALANAESTHETICTORELIEVE pain) s ERGOTAMINEUSEDTOTREATMIGRAINE s MEDICINESTOTREATOTHERMENTALILLNESSESSUCH as phenothiazines) s ANTIRETROVIRALDRUGSEGRITONAVIR USEDTOTREAT AIDS and some other conditions s DRUGSTOPREVENTMALARIA s MEDICINESTOTREATFUNGALINFECTIONS s ADRENALINEUSEDINEMERGENCYTREATMENTEG allergic reactions) s INDOMETACINANDCELECOXIBUSEDTOTREAT inflammation of the joints, gout and period pain) medicines for the treatment of diabetes (including insulin). Your doctor may need to adjust your dose of these medicines. Tell your doctor or pharmacist if you are taking, have recently taken or might take other medicines, including medicines obtained without a prescription. 4AKING-ETOPROLOLWITHFOODDRINKANDALCOHOL You should keep your alcohol intake to a minimum while you are taking Metoprolol, as alcohol may increase the effect of this drug. 0REGNANCYBREAST FEEDINGANDFERTILITY )FYOUAREPREGNANTORBREAST FEEDINGTHINKYOU may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. $RIVINGANDUSINGMACHINES Metoprolol may cause dizziness and tiredness, if affected do not drive or operate machinery. Read the complete document
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE MEDICINAL PRODUCT Metoprolol Tartrate 100 mg Tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains 100 mg of metoprolol tartrate. Excipient(s) with known effect: Each tablet contains 166 mg of lactose. For the full list of excipients, see 6.1. 3 PHARMACEUTICAL FORM Round, biconvex white tablet, engraved 4A6 with a breakline on reverse. 4. CLINICAL PARTICULARS 4.1. THERAPEUTIC INDICATIONS Metoprolol tablets are indicated for the management of hypertension, angina pectoris and cardiac arrhythmias, especially supraventricular tachyarrhythmias. They may also be used as an adjunct in the treatment of hyperthyroidism. In the early treatment of acute myocardial infarction, metoprolol may be used to reduce infarct size and the incidence of ventricular fibrillation. By providing pain relief, the need for opiate analgesics may be decreased. When administered to patients with acute myocardial infarction, metoprolol has been demonstrated to reduce mortality. Metoprolol is also indicated for the prevention of migraine. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Posology The dose must always be adjusted to the individual requirements of the patient but should not exceed 400mg/day. The following are guidelines: Adults The usual dosage for the following indications is given below. Hypertension: The initial dosage is 100 mg per day in the morning, which may be increased by 100 mg per day at weekly intervals to a maximum of 400 mg per day, depending on response. If control is not achieved with a single daily dose, twice daily dosing should be initiated. Over the dosage range most patients may be expected to respond rapidly and satisfactory. Combination therapy with a diuretic or another hypotensive agent may also be considered to attain a further reduction in blood pressure. Metoprolol may be administered with benefit both to previously untreated patients with hypertension and to those in whom the response to previous therapy is inadequate. In the latter type of pat Read the complete document