MELOXICAM RANBAXY

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Meloxicam

Available from:

Ranbaxy Australia Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

MELOXICAM RANBAXY 
Meloxicam Ranbaxy CMI V3 May 2010

                Page 1 of 4

_MELOXICAM TABLETS_  

CONSUMER MEDICINE INFORMATION 

WHAT IS IN THIS LEAFLET 

This leaflet answers some 
common questions about 
MELOXICAM RANBAXY. It does not 
contain all available information, 
nor does it take the place of 
talking to your doctor or 
pharmacist.  

Keep this leaflet with this 
medicine. You may need to read it 
again later. 

You should ask your doctor or 
pharmacist if you have any 
questions about MELOXICAM 
RANBAXY or if you have any 
trouble before, during or after 
taking MELOXICAM RANBAXY. 

WHAT MELOXICAM RANBAXY IS 
USED FOR 

MELOXICAM RANBAXY is used to 
treat the symptoms of: 
 osteoarthritis 
 rheumatoid 
arthritis 

Although MELOXICAM RANBAXY 
can relieve symptoms such as 
pain and inflammation, it will not 
cure your condition. 

MELOXICAM RANBAXY belongs to a 
family of medicines called Non-
Steroidal Anti-inflammatory Drugs 
(NSAIDs). These medicines work 
by relieving pain and 
inflammation. 

Ask your doctor if you have any 
questions about why MELOXICAM 
RANBAXY has been prescribed for 
you. Your doctor may have 
prescribed MELOXICAM RANBAXY 
for another reason. 

BEFORE YOU TAKE MELOXICAM 
RANBAXY 

WHEN YOU MUST NOT TAKE 
MELOXICAM RANBAXY 
Do not take MELOXICAM RANBAXY 
if you have an allergy to: 
-  the active ingredient, 
meloxicam, lactose or any of 
the other ingredients in 
MELOXICAM RANBAXY (all of 
these ingredients are listed at 
the end of this leaflet) 
-  aspirin or any other NSAID 
medicine 

Some of the symptoms of an 
allergic reaction may include: 
  rash, itching or hives on the 
skin 
  swelling of the face, lips, 
tongue or other parts of the 
body 
  shortness of breath, wheezing 
or trouble breathing 

If you are not sure if you have 
these allergies, you should raise 
those concerns with your d

Summary of Product characteristics

Ranbaxy Australia Pty Ltd 

Meloxicam Ranbaxy PI 
MELOXICAM RANBAXY PI V2 May10

Page 1 of 16

MELOXICAM RANBAXY PRODUCT INFORMATION 

COMPOSITION  
Meloxicam 
DESCRIPTION  
Chemical
names: 4-hydroxy-2-methyl-_N_-(5-methyl-2-thiazolyl)-2_H_-1,2-benzothiazine-3- 
carboxamide-1,1-dioxide and 2_H_-1,2-benzothiazine-3-carboxamide,4-hydroxy-2-methyl-_N_-(5 
methyl-2-thiazolyl)-1,1-dioxide.  

Molecular formula: C
14
H
13
N
3
O
4
S
2
.  
MW: 351.4.  
CAS: 71125-38-7. 

Meloxicam is a pale yellow powder with pKa values
of 1.09 and 4.18 and a melting point of about 
256 deg. C. The substance is practically insoluble
in water, soluble in dimethylformamide, slightly 
soluble in chloroform and acetone and very slightly soluble in
methanol. There are no chiral 
centres and no polymorphs are formed under normal conditions. 

Meloxicam Ranbaxy tablets contain the following excipients:
microcrystalline cellulose, 
pregelatinised maize starch, lactose, starch- maize, sodium
citrate, silica colloidal anhydrous, 
magnesium stearate. 
PHARMACOLOGY 
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) of
the enolic acid class, which has 
shown anti-inflammatory, analgesic and antipyretic
properties in animals. Meloxicam showed anti-
inflammatory activity in all standard models of inflammation.
A common mechanism for the above 
effects may exist in the ability of meloxicam to inhibit the
biosynthesis of prostaglandins, known 
mediators of inflammation,
by inhibition of cyclooxygenase (COX). 

Comparison of the ulcerogenic dose and
the anti-inflammatory effective dose in rat adjuvant 
arthritis confirmed a greater therapeutic margin in
animals over other NSAIDs (piroxicam, 
diclofenac, naproxen, flurbiprofen). In rats,
meloxicam showed greater inhibitory effect on 
prostaglandin biosynthesis at the site of inflammation than in
the gastric mucosa or the kidney. 

Selective i