Mayne Pharma Erythromycin

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Erythromycin

Available from:

Mayne Pharma International Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

 
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MAYNE PHARMA ERYTHROMYCIN 
CAPSULES

erythromycin _(eh-rith-roe-MYE-sin) _
_ _

CONSUMER MEDICINE INFORMATION 
_Date of Dispensing _
_Consumer Name _
_Pharmacist Name _
_Consumer Address _
_Pharmacist Address _

WHAT IS IN THIS LEAFLET 

This leaflet answers some common 
questions about Mayne Pharma 
Erythromycin Capsules. It does not 
contain all the available information. 
It does not take the place of talking 
to your doctor or pharmacist. 

All medicines have risks and 
benefits.  Your doctor has weighed 
the risks of you taking erythromycin 
against the benefits they expect it 
will have for you. 

IF YOU HAVE ANY CONCERNS ABOUT 
TAKING THIS MEDICINE, ASK YOUR 
DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET WITH THE 
MEDICINE. 
You may need to read it again. 

WHAT  ERYTHROMYCIN 
CAPSULES ARE USED FOR 

This medicine is an antibiotic used 
to: 
  treat infections in different parts 
of the body caused by bacteria 
  prevent infections in patients 
with a history of rheumatic 
disease who may be allergic to 
penicillin. 

This medicine is an antibiotic which 
belongs to a group of medicines 
called macrolides. 

It works by killing or stopping the 
growth of bacteria which cause 
infections. 

This medicine will not work against 
viral infections such as colds or flu. 

ASK YOUR DOCTOR IF YOU HAVE ANY 
QUESTIONS ABOUT WHY THIS  
MEDICINE HAS BEEN PRESCRIBED FOR 
YOU. 
Your doctor may have prescribed it 
for another reason. 

This medicine is not addictive. 

This medicine is available only with 
a doctor’s prescription. 

BEFORE YOU TAKE 
ERYTHROMYCIN CAPSULES 
_ _
_WHEN YOU MUST NOT TAKE IT _

DO NOT TAKE ERYTHROMYCIN 
CAPSULES IF YOU HAVE AN ALLERGY 
TO: 
  any medicine containing 
erythromycin 
  any of the ingredients listed at 
the end of this leaflet. 

Some of the symptoms of an 
allergic reaction may include 
shortness of breath, wheezing or

Summary of Product characteristics

Product Information – Australia 

Version 2.0 

Page  1 
MAYNE PHARMA ERYTHROMYCIN CAPSULES 

NAME OF THE MEDICINE 
The active ingredient in Mayne Pharma Erythromycin Capsules is
erythromycin. 

The chemical structure of erythromycin is shown below 

CAS No. 114-07-8 

DESCRIPTION 
Mayne Pharma Erythromycin Capsules contain enteric coated pellets of
erythromycin for oral 
administration.  The enteric coating on the pellets covers the
bitter tasting erythromycin as well as protects 
the erythromycin from gastric acid destruction during the passage
through the stomach.   

Mayne Pharma Erythromycin Capsules also contain the
following inactive ingredients: lactose, 
potassium phosphate monobasic, povidone, water-purified, cellacephate,
diethyl phthalate, gelatine, 
shellac, erythrosine, indigo carmine (132), sunset yellow (110),
carbon black (153). 

Erythromycin is produced by a strain of _Streptomyces erythreus_ and
belongs to the macrolide group of 
antibiotics.  It is basic and readily forms salts with acids. 

CLINICAL PHARMACOLOGY 
Orally administered erythromycin is readily absorbed in the
microbiologically active form.  Interindividual 
variations in the absorption of erythromycin are, however, observed
and some patients do not achieve 
acceptable serum levels.  Absorption may be interfered with by the
presence of food in the stomach.  
Optimal conditions for stability in the presence of gastric secretion
and for complete absorption are 
attained when Mayne Pharma Erythromycin Capsules are taken on an
empty stomach. 

After administration of the third dose of 2 x 175mg erythromycin
capsules to adults, a mean peak serum 
level of 2.01 ± 0.69mcg/ml was attained in approximately 2-4 hours.
 This is comparable to peak serum 
levels achieved with 2 x 250mg of other formulations of erythromycin.
 Erythromycin is bound to plasma 
proteins to the extent of approximately 75%.  It diffuses readily
into most body fluids