MARBOCYL P TABLET 5MG

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

MARBOFLOXACIN

Available from:

Gladron Chemicals Sdn Bhd

INN (International Name):

MARBOFLOXACIN

Units in package:

100.00 mcg/mL; 10.00 mcg/mL

Manufactured by:

Vetoquinol

Summary of Product characteristics

_Veterinary Pharmaceuticals_
Magny-Vernois 70200 Lure (France)
_DIMENSIONS : 160x120 mm_
_RÉFÉRENCE ARTICLE : _
_0510 G_
_NOM DU PRODUIT :_
_Marbocyl 5/20/80 MALAISIE_
_1 COULEUR_
_BLEU NUIT 281 U_
_CRÉÉ PAR : P. Mougenot_
_LE : 13/03/2012_
_VISA :_
_REV G_
_VÉTOQUINOL _
USES
PHARMACODYNAMIC PROPERTIES:
MARBOFLOXACIN is a synthetic, bactericidal antimicrobial, belonging to
the fluoroquinolone group which acts by inhibition of the DNA gyrase.
It is effective against a wide range of Gram positive bacteria (in
particu-
lar _Staphylococci, Streptococci_) and Gram negative bacteria
(_Escherichia_
_coli, Salmonella typhimurium, Citrobacter freundii, Enterobacter
cloacae,_
_Serratia marcescens, Morganella morganii, Proteus spp, Klebsiella
spp,_
_Shigella _
_spp, _
_Pasteurella _
_spp, _
_Haemophilus _
_spp, _
_Moraxella _
_spp,_
_Pseudomonas _
_spp, _
_Brucella _
_canis_)
as
well
as
_Mycoplasma _
_spp._
Marbofloxacin is not active against anaerobes, yeasts or fungi.
PHARMACOKINETIC PROPERTIES :
After oral administration in dogs and cats at the recommended dose of
2 mg/kg, MARBOFLOXACIN is readily absorbed and reaches maximal
plasma concentrations of 1.5 µg/ml within 2 hours.
Its bioavailability is close to 100 %.
It is weakly bound to plasma proteins (less than 10 %), extensively
distri-
buted and in most tissues (liver, kidney, skin, lung, bladder,
digestive
tract) it achieves higher concentrations than in plasma. MARBOFLOXACIN
is eliminated slowly (t1/2ß= 14 h in dogs and 10 h in cats) predomi-
nantly in the active form in urine (2/3) and faeces (1/3).
INDICATIONS
Marbocyl P is indicated in the treatment of:
IN DOGS :
- Skin and soft tissue infections (skinfold pyoderma, impetigo,
folliculitis,
furunculosis,
cellulitis)
caused
by
susceptible
strains
of
organisms.
OPERATOR WARNINGS
People with known hypersensitivity to fluoroquinolones should avoid
using this product. In case of accidental ingestion, seek medical
atten-
tion and show product label and/or package leaflet to the doctor. Wear
gloves when handling o