LONCOR 300- florfenicol solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

FLORFENICOL (UNII: 9J97307Y1H) (FLORFENICOL - UNII:9J97307Y1H)

Available from:

Bayer HealthCare, LLC Animal Health Division

INN (International Name):

FLORFENICOL

Composition:

FLORFENICOL 300 mg in 1 mL

Administration route:

INTRAMUSCULAR

Prescription type:

PRESCRIPTION

Therapeutic indications:

LONCOR™ 300 is indicated for treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica , Pasteurella multocida , and Histophilus somni , and for the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus . Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica , Pasteurella multocida , and Histophilus somni . Do not use in animals that have shown hypersensitivity to florfenicol. This product contains materials that can be irritating to skin and eyes. Avoid direct contact with skin, eyes, and clothing. In case of accidental eye exposure, flush with water for 15 minutes. In case of accidental skin exposure, wash with soap and water. Remove contaminated clothing. Consult a physician if irritation persists. Accidental injection of this product may cause local irritatio

Product summary:

Loncor™ 300 is packaged in 250 mL and 500 mL glass sterile multiple-dose vials.

Authorization status:

Abbreviated New Animal Drug Application

Summary of Product characteristics

LONCOR 300- FLORFENICOL SOLUTION
BAYER HEALTHCARE, LLC ANIMAL HEALTH DIVISION
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LONCOR 300
(FLORFENICOL)
300 MG/ML INJECTABLE SOLUTION
FOR INTRAMUSCULAR AND SUBCUTANEOUS USE IN BEEF AND NON-LACTATING DAIRY
CATTLE ONLY
NOT FOR USE IN FEMALE DAIRY CATTLE 20 MONTHS OF AGE OR OLDER OR IN
CALVES TO
BE PROCESSED FOR VEAL
CAUTION
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION
LONCOR™ 300 (florfenicol) 300 mg/mL Injectable Solution is a
solution of the synthetic
antibiotic florfenicol. Each milliliter of sterile LONCOR™ 300
contains 300 mg of
florfenicol, 250 mg n-methyl-2-pyrrolidone, 150 mg propylene glycol,
and polyethylene
glycol qs.
INDICATIONS
LONCOR™ 300 is indicated for treatment of bovine respiratory disease
(BRD) associated
with _Mannheimia haemolytica_, _Pasteurella multocida_, and
_Histophilus somni_, and for the
treatment of bovine interdigital phlegmon (foot rot, acute
interdigital necrobacillosis,
infectious pododermatitis) associated with _Fusobacterium necrophorum
_and _Bacteroides_
_melaninogenicus_. Also, it is indicated for the control of
respiratory disease in cattle at
high risk of developing BRD associated with _Mannheimia haemolytica_,
_Pasteurella_
_multocida_, and _Histophilus somni_.
DOSAGE AND ADMINISTRATION
FOR TREATMENT OF BOVINE RESPIRATORY DISEASE (BRD) AND BOVINE
INTERDIGITAL
PHLEGMON (FOOT ROT): LONCOR™ 300 should be administered by
intramuscular
injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100
lbs). A second dose
should be administered 48 hours later. Alternatively, LONCOR™ 300
can be
administered by a single subcutaneous (SC) injection to cattle at a
dose rate of 40 mg/kg
body weight (6 mL/100 lbs). Do not administer more than 10 mL at each
site. The
injection should be given only in the neck.
NOTE: Intramuscular injection may result in local tissue reaction
which persists beyond
28 days. This may result in trim loss of edible tissue at slaughter.
Tissue reaction at
injection sites other than the