LIGNOCAINE HYDROCHLORIDE INJECTION BP 1% (WITHOUT PRESERVATIVE)

Country: Singapore

Language: English

Source: HSA (Health Sciences Authority)

Active ingredient:

LIGNOCAINE HCl

Available from:

DCH AURIGA SINGAPORE

ATC code:

N01BB02

Dosage:

10 mg/ml

Pharmaceutical form:

INJECTION

Composition:

LIGNOCAINE HCl 10 mg/ml

Administration route:

INTRAVENOUS

Prescription type:

Prescription Only

Manufactured by:

PFIZER (PERTH) PTY LTD

Authorization status:

ACTIVE

Authorization date:

1991-04-08

Summary of Product characteristics

LIGNOCAINE
INJECTION
(LIDOCAINE
(LIGNOCAINE)
HYDROCHLORIDE
MONOHYDRATE)
1.
NAME OF THE MEDICINE
Lignocaine Hydrochloride Injection BP 1% (without preservative)
Lignocaine Injection 2% (without preservative)
2.
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each
ml
of
Lignocaine
Injection
contains
10
mg
or
20
mg
lidocaine
(lignocaine)
hydrochloride monohydrate.
For the full list of excipients, see section 6.1 List of excipients.
3.
PHARMACEUTICAL FORM
Solution for injection.
Lignocaine Injection is a clear, colourless, sterile, isotonic,
preservative-free solution.
4.
CLINICAL PARTICULARS
4.1 THERAPEUTIC INDICATIONS
Lidocaine (lignocaine) is indicated for production of local or
regional anaesthesia by nerve
block, infiltration injection, caudal or other epidural blocks.
Treatment
or
prophylaxis
of
life-threatening
ventricular
arrhythmias,
including
those
associated
with
myocardial
infarction,
general
anaesthesia
in
patients
predisposed
to
ventricular arrhythmias, digitalis intoxication, or following
resuscitation from cardiac arrest.
4.2
DOSE AND METHOD OF ADMINISTRATION
DOSAGE
_AS A LOCAL ANAESTHETIC FOR INFILTRATION AND NERVE BLOCK: _
The dosage varies and depends upon the area to be anaesthetised,
vascularity of the tissues,
number of neuronal segments to be blocked, individual tolerance and
the technique of
anaesthesia. The lowest dose needed to provide effective anaesthesia
should be administered.
For specific techniques and procedures, refer to standard textbooks.
It is recommended that the dose of lidocaine (lignocaine) at any one
time should not exceed
3 mg/kg. However, the dose administered must be tailored to the
individual patient and
procedure, and the maximum doses here quoted should be used as a guide
only.
The normal recommended dose of lidocaine (lignocaine) for various
anaesthetic procedures
in an average, healthy 70 kg adult patient are as follows:
PROCEDURE
CONCENTRATION (%)
VOLUME (ML)
DOSE (MG)
Infiltration
1.0
20
200
PERIPHERAL NERVE BLOCKS
Paravertebral
1.0
3 - 5
30 - 50
Pudendal (each side)
1.0
1