LACTATED RINGER- sodium chloride, potassium chloride, calcium chloride and sodium lactate injection, solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

SODIUM CHLORIDE (UNII: 451W47IQ8X) (SODIUM CATION - UNII:LYR4M0NH37, CHLORIDE ION - UNII:Q32ZN48698), POTASSIUM CHLORIDE (UNII: 660YQ98I10) (POTASSIUM CATION - UNII:295O53K152, CHLORIDE ION - UNII:Q32ZN48698), CALCIUM CHLORIDE (UNII: M4I0D6VV5M) (CALCIUM CATION - UNII:2M83C4R6ZB, CHLORIDE ION - UNII:Q32ZN48698), SODIUM LACTATE (UNII: TU7HW0W0QT) (SODIUM CATION - UNII:LYR4M0NH37, LACTIC ACID - UNII:33X04XA5AT)

Available from:

ASPEN VETERINARY

Administration route:

INTRAVENOUS

Prescription type:

PRESCRIPTION

Therapeutic indications:

Lactated Ringer Injection is indicated as a source of water and electrolytes for all species. It is also used as an alkalinizing agent. Lactated Ringer Injection is contraindicated in patients with a known hypersensitivity to sodium lactate; congestive heart failure or severe impairment of renal function; clinical states in which the administration of sodium and chloride is detrimental.

Authorization status:

unapproved drug other

Summary of Product characteristics

LACTATED RINGER- SODIUM CHLORIDE, POTASSIUM CHLORIDE, CALCIUM CHLORIDE
AND SODIUM
LACTATE INJECTION, SOLUTION
ASPEN VETERINARY
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
----------
LACTATED RINGER
STERILE NONPYROGENIC SOLUTION
FOR ANIMAL USE ONLY
DES CRIPTION
Lactated Ringer Injection is a sterile, non-pyrogenic solution
intended for fluid and electrolyte
replenishment in single dose containers. May be administered
intravenously, subcutaneously or
intraperitoneally (except in horses) using aseptic technique. It
contains no antimicrobial agents. Discard
any unused portion. Composition, osmolarity, pH and ionic
concentration are shown in Table 1.
TABLE 1
*Sodium Lactate USP – (S)-enantiomer
Osmolarity (mOsmol/L) (calc): 273mOsmol per liter
pH: 6.5 (limit 6.0 – 7.5)
The container is free of PVC and phthalates. The container meets the
requirements of USP and is
registered with FDA.
CLINICAL PHARMACOLOGY
A multiple electrolyte intravenous solution is intended to restore the
electrolyte balance and water for
hydration. A combination of multiple electrolytes and sodium lactate,
an alkalinizing agent, will provide
electrolyte balance and normalize the pH of the acid-base of the
physiological system.
INDICATIONS
Lactated Ringer Injection is indicated as a source of water and
electrolytes for all species. It is also
used as an alkalinizing agent.
CONTRAINDICATIONS
Lactated Ringer Injection is contraindicated in patients with a known
hypersensitivity to sodium lactate;
congestive heart failure or severe impairment of renal function;
clinical states in which the
administration of sodium and chloride is detrimental.
WARNINGS
The introduction of additives to any solution, regardless of type of
container, requires special attention
to ensure that no incompatibilities result. While some
incompatibilities are readily absorbed, one must
be aware that subtle physical, chemical and pharma