Kordel's Super Garlic 20,000

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Garlic Oil

Available from:

Catalent Australia Pty Ltd

INN (International Name):

Garlic Oil

Class:

Medicine Listed

Authorization status:

Listed

Patient Information leaflet

AZOL
1
AZOL
_contains the active ingredient danazol_
CONSUMER MEDICINE INFORMATION
WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Azol.
It does not contain all of the
available information. It does not
take the place of talking to your
doctor or pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you taking Azol against the
benefits expected for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, TALK TO YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH YOUR
MEDICINE.
You may need to read it again.
WHAT AZOL IS USED FOR
Azol is used in the following
conditions:
*
Endometriosis - a condition in
which tissue similar to the lining
of the uterus (womb) grows
outside the uterus causing pain or
bleeding
*
Menorrhagia - abnormally heavy
during menstruation
*
Severe fibrocystic breast disease -
lumps or cysts in the breast
which are very painful
*
Hereditary angioedema - an
inherited condition associated
with repeated episodes of
stomach upset and swelling of the
throat.
Azol contains the active ingredient
danazol, which alters the level or the
way certain chemicals in the body
work.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY AZOL HAS BEEN
PRESCRIBED FOR YOU.
Your doctor may have prescribed
Azol for another reason.
Azol is not recommended for use in
children, as the safety and
effectiveness in children has not been
established.
Azol is available only with a doctor's
prescription.
There is no evidence that Azol is
addictive.
BEFORE YOU TAKE AZOL
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE AZOL IF YOU ARE ALLERGIC
TO MEDICINES CONTAINING DANAZOL
(E.G. DANOCRINE) OR ANY OF THE
INGREDIENTS LISTED AT THE END OF THIS
LEAFLET.
Some of the symptoms of an allergic
reaction may include hayfever, skin
rash, itching or hives.
DO NOT TAKE AZOL IF YOU HAVE ANY OF
THE FOLLOWING MEDICAL CONDITIONS:
*
severe liver, kidney or heart
disease
*
very high blood pressure
*
pelvic infection
*
porphyria - a blood disorder
*
previous or present blockage of a
blood vessel by

Summary of Product characteristics

AZOL
_Danazol_
PRODUCT INFORMATION
NAME OF THE MEDICINE
Active ingredient: Danazol
Chemical name: 17
α
-pregna-2,4-dien-20-yno(2,3-d)isoxazol-17
β
-ol
Structural formula:
Molecular formula: C
22
H
27
NO
2
Molecular weight: 337.5
CAS Registry No.: 17230-88-5
DESCRIPTION
Danazol is a synthetic hormone derived from ethisterone.
Danazol is a white or pale yellow crystalline powder. It is
practically insoluble in water, but soluble in
chloroform and in acetone. It has a melting point of 225°C with some
decomposition.
Each Azol 100 capsule contains 100 mg of danazol. Azol 100 capsules
also contain the following inactive
ingredients: lactose, cellulose – microcrystalline, silica -
colloidal anhydrous, povidone, lactose anhydrous,
sodium starch glycollate, sodium lauryl sulfate, magnesium stearate,
titanium dioxide, gelatin, iron oxide
black.
Each Azol 200 capsule contains 200 mg of danazol. Azol 200 capsules
also contains the following inactive
ingredients: lactose anhydrous, erythrosine, lactose, sodium lauryl
sulfate, iron oxide red, silica - colloidal
anhydrous, sodium starch glycollate, cellulose – microcrystalline,
titanium dioxide, povidone, magnesium
stearate, gelatin, iron oxide yellow.
PHARMACOLOGY
_Endometriosis and Menorrhagia._
In women of reproductive age, danazol suppresses the pituitary-ovarian
axis.
This suppression is probably a combination of depressed
hypothalamic-pituitary response to lowered oestrogen
production, the alteration of sex steroid metabolism, and the
interaction of danazol with sex hormone receptors.
The only other demonstrable hormonal effect is weak androgenic
activity and associated anabolic activity. No
significant oestrogenic or progestational activity attributable to
danazol has been found.
Danazol depresses the output of both follicle-stimulating hormone
(FSH) and luteinising hormone (LH).
In the treatment of endometriosis, danazol alters the normal and
ectopic endometrial tissue so that it becomes
inactive and atrophic. Complete resolution of endometrial lesions
occurs in