Country: Malaysia
Language: English
Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Chondroitin Sulphate; Glucosamine Sulfate Potassium Chloride
CAMBERT(M) SDN BHD
Chondroitin Sulphate; Glucosamine Sulfate Potassium Chloride
90Capsule Capsules; 60Capsule Capsules; 50Capsule Capsules; 75Capsule Capsules; 30Capsule Capsules
Vitaco Health (NZ) Ltd.
KORDEL’S GLUCOSAMINE PLUS CHONDROITIN 500/400 CAPSULE Glucosamine sulfate / chondroitin sulfate (500mg/400mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What Kordel’s Glucosamine Plus Chondroitin Capsule_ _is used for 2. How Kordel’s Glucosamine Plus Chondroitin Capsule works 3. Before you use Kordel’s Glucosamine Plus Chondroitin Capsule 4. How to use Kordel’s Glucosamine Plus Chondroitin Capsule 5. While you are using it 6. Side effects _7._ _ _ Storage and disposal of Kordel’s Glucosamine Plus Chondroitin Capsule_ _ 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT KORDEL’S GLUCOSAMINE PLUS CHONDROITIN CAPSULE IS USED FOR Kordel’s Glucosamine Plus Chondroitin Capsule is used as adjuvant therapy for osteoarthritis (degenerative joint disease characterized by joint pain and stiffness). HOW KORDEL’S GLUCOSAMINE PLUS CHONDROITIN CAPSULE WORKS Kordel’s Glucosamine Plus Chondroitin Capsule helps to improve joint function, builds up the cartilage and also promotes the production of synovial fluid (the fluid confined within a joint space and acts as a lubricant). Both Glucosamine and Chondroitin work synergistically and helps to reduce joint pain, improve joint function & flexibility and to delay the joint degeneration. BEFORE YOU USE KORDEL’S GLUCOSAMINE PLUS CHONDROITIN CAPSULE - _When you must not use it _ Do not take Kordel’s Glucosamine Plus Chondroitin Capsule if you are hypersensitive to glucosamine, chondroitin or shellfish. Kordel’s Glucosamine Plus Chondroitin Capsule is derived from seafood. - _Before you start to use it _ Tell your doctor or pharmacist before using glucosamine and chondroitin if you: 1) Are pregnant or plan to get pregnant. 2) Are breast-feeding or plan to start breast-feeding. 3) Have diabetes or any health problem. - _Taking other medicines _ Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or he Read the complete document
KORDEL’S GLUCOSAMINE CHONDROITIN 500/400 CAPSULE COMPOSITION Each capsule contains glucosamine sulphate potassium chloride complex equivalent to Glucosamine sulphate 500mg and Chondroitin sulphate 400mg. INDICATION As an adjunct therapy for osteoarthritis. PHARMACOLOGY AND MECHANISM OF ACTION Osteoarthritis, or degenerative joint disease, is seen mainly, but not exclusively, in the elderly. This condition occurs when there is breakdown and damage of joint cartilage, followed by hardening and formation of bone spurs in the joint margins. Symptoms of osteoarthritis include joint pain and joint stiffness. Glucosamine stimulates the biosynthesis of proteoglycans, which are fundamental components of aggrecan found in articular cartilage. Aggrecan confers on cartilage its high shock‐absorbing properties and resilience vital for proper joint function. Glucosamine also inhibits enzymes involved in cartilage degradation. In addition, glucosamine improves synovial fluid production and viscosity, giving better lubricant activity for the joints. Chondroitin sulphate, as a vital component of aggrecan, helps to maintain the structural integrity of cartilage tissue. Loss of chondroitin sulphate from the joint cartilage leads to loss of cartilage resilience and shock‐absorbing properties. Orally administered chondroitin sulphate leads to increases in hyaluronic acid production and viscosity of synovial fluid. Chondroitin sulphate also inhibits enzymes involved in degradation of cartilage. Combination therapy with glucosamine and chondroitin helps to protect joint cartilage from damage (chondroprotection), reduces joint pain and improves joint function and mobility. Glucosamine/chondroitin combination is effective in all forms of degenerative joint diseases such as osteoarthritis and arthrosis, both acute and chronic, bringing relief or reduction of joint pains, improvement in joint function and inhibition or reversal of the degenerative disease process. PHARMACOKINETICS Following oral administration, glucosamine sulphate i Read the complete document