IVERMAX POUR-ON FOR CATTLE- ivermectin cattle pour-on solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D)

Available from:

ASPEN VETERINARY RESOURCES, LTD.

INN (International Name):

IVERMECTIN

Composition:

IVERMECTIN 5 mg in 1 mL

Administration route:

TOPICAL

Prescription type:

OTC

Therapeutic indications:

Ivermax® Pour-On for Cattle applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites. Gastrointestinal Roundworms Ostertagia ostertagi (including inhibited stage)       (adults and L4) Haemonchus placei                                                 (adults and L4) Tr ichostrongylus axei                                               (adults and L4) T. colubriformis                                                        (adults and L4) Cooperia oncophora                                                 (adults and L4) Cooperia punctate                                                   (adults and L4) Cooperia surnabada                                                (adults and L4) Strongyloides papillosu                                           (adults) Oesophagostomum radiatum                                  (adults and L4) Trichuris spp.                                                         (adults) Lungworms Di

Product summary:

Ivermax® Pour-On for Cattle is available in 250 mL (8.5 fl oz) and 1 L (33.8 fl oz) tip and measure bottles, and 2.5 L (84.5 fl oz), 5 L (169.0 fl oz), and 5 Gallon (639.0 fl oz) containers for use with an appropriate automatic dosing applicator. Manufactured for: Aspen Veterinary Resources,® Ltd. Liberty, MO 64068, USA A190FP 12/20 www.aspenveterinaryresources.com

Authorization status:

Abbreviated New Animal Drug Application

Summary of Product characteristics

IVERMAX POUR-ON FOR CATTLE- IVERMECTIN CATTLE POUR-ON SOLUTION
ASPEN VETERINARY RESOURCES, LTD.
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IVERMAX POUR-ON FOR CATTLE
(IVERMECTIN TOPICAL SOLUTION)
5 mg ivermectin/mL
PARASITICIDE
Kills: Roundworms (including Brown Stomach Worm), Lungworms, Grubs,
Sucking Lice,
Biting Lice, Mange Mite, Horn Flies
WARNING! FLAMMABLE! KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME AND
OTHER SOURCES OF IGNITION.
Restricted Drug (California) – Use Only as Directed.
FOR ANIMAL USE ONLY
KEEP OUT OF REACH OF CHILDREN
Approved by FDA under ANADA # 200-340
See attached booklet for complete indications and use directions.
PARASITICIDE
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT
AND
CONTROL OF PARASITISM.
INTRODUCTION
Ivermax
Pour-On for Cattle (ivermectin topical solution) delivers internal and
external
parasite control in one convenient low-volume application. Ivermax
Pour-On for Cattle
contains ivermectin, a unique chemical entity.
MODE OF ACTION
Ivermectin is a member of the macrocylic lactone class of endectocides
which have a
unique mode of action. Compounds of the class bind selectively and
with high affinity to
glutamate-gated chloride ion channels which occur in invertebrate
nerve and muscle
cells.
This leads to an increase in the permeability of the cell membrane to
chloride ions with
hyperpolarization of the nerve or muscle cell, resulting in paralysis
and death of the
parasite. Compounds of this class may also interact with other
ligand-gated chloride
channels, such as those gated by the neurotransmitter
gamma-aminobutyric acid
(GABA).
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®
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The margin of safety for compounds of this class is attributable to
the fact that
mammals do not have glutamate-gated chloride channels, the macrocyclic
lactones have
a low affinity for other mammalian ligand-gated chloride channels and
they do not readily
cross the blood-brain barrier.
INDICATIONS
Ivermax
Pour-On for Cattle applied at the recommended dose level of 500 mcg/kg
is
indicated for the effective treatment and control of these parasites.
GASTR