ISOPTIN SR TABLET 240 mg

Country: Singapore

Language: English

Source: HSA (Health Sciences Authority)

Active ingredient:

Verapamil Hydrochloride

Available from:

ABBOTT LABORATORIES (SINGAPORE ) PRIVATE LIMITED

ATC code:

C08DA01

Dosage:

240 mg

Pharmaceutical form:

TABLET, FILM COATED

Composition:

Verapamil Hydrochloride 240.0 mg

Administration route:

ORAL

Prescription type:

Prescription Only

Manufactured by:

AbbVie Deutschland GmbH & Co. Kg

Authorization status:

ACTIVE

Authorization date:

1988-04-22

Patient Information leaflet

CCDS1000326220  
Updated: 12/2/2014 

ISOPTIN
®
 SR 240MG 
ACTIVE DRUG SUBSTANCE: VERAPAMIL HYDROCHLORIDE  
FILM COATED TABLETS WITH PROLONGED ACTION  
CALCIUM ANTAGONIST FOR THE TREATMENT OF HYPERTENSION  
QUALITATIVE AND QUANTITATIVE COMPOSITION 
Verapamil hydrochloride is a calcium
ion influx inhibitor (slow channel blocker or calcium ion
antagonist). The chemical name of verapamil hydrochloride is 
benzeneacetonitrile, α-[3-[{2-(3,
4-dimethoxyphenyl) ethyl} methylamino]
propyl]-3,4-dimethoxy-α-(1-methylethyl) hydrochloride. It
has a molecular weight 
of 491.07 and the molecular formula is C27H38N204•HCl. 

COMPOSITION  
1 film coated tablet contains 240mg
of verapamil hydrochloride.  

PHARMACEUTICAL FORM 

Verapamil hydrochloride is a calcium
ion influx inhibitor (slow channel blocker or calcium
ion antagonist). Verapamil hydrochloride is an almost white, 
crystalline powder, practically free of odor, with a bitter
taste. It is soluble in water, freely soluble in chloroform,
sparingly soluble in alcohol and practically 
insoluble in ether.  

CLINICAL PARTICULARS 

THERAPEUTIC INDICATIONS 
Hypertension  

POSOLOGY AND METHOD OF ADMINISTRATION 
The doses of Isoptin SR 240mg, individualized
according to the severity of the disease, are to be taken
regularly as prescribed by the physician. The film 
coated tablets are to be swallowed whole
with some fluid, preferably with or shortly after meals. Unless otherwise instructed, the daily dose
for adults is 1 
film coated tablet in the morning (patients
requiring particularly gradual blood pressure lowering should be started on half tablet taken in the
morning). If 
after about 2 weeks of treatment a dose increase is found
to be necessary the dose can be raised to a maximum of
2 film coated tablets daily (additionally 
1 half to 1 film coated tablet in

Summary of Product characteristics

RDCCDS000462/13
Updated: 15-Oct-20
ISOPTIN
®
SR 240MG
ACTIVE DRUG SUBSTANCE: VERAPAMIL HYDROCHLORIDE
FILM COATED TABLETS WITH PROLONGED ACTION
CALCIUM ANTAGONIST FOR THE TREATMENT OF HYPERTENSION
QUALITATIVE AND QUANTITATIVE COMPOSITION
Verapamil hydrochloride is a calcium ion influx inhibitor (slow
channel blocker or calcium ion antagonist). The chemical name of
verapamil hydrochloride is
benzeneacetonitrile, α-[3-[{2-(3, 4-dimethoxyphenyl) ethyl}
methylamino] propyl]-3,4-dimethoxy-α-(1-methylethyl) hydrochloride.
It has a molecular weight
of 491.07 and the molecular formula is C27H38N204•HCl.
COMPOSITION
1 film coated tablet contains 240mg of verapamil hydrochloride.
PHARMACEUTICAL FORM
Verapamil hydrochloride is a calcium ion influx inhibitor (slow
channel blocker or calcium ion antagonist). Verapamil hydrochloride is
an almost white,
crystalline powder, practically free of odor, with a bitter taste. It
is soluble in water, freely soluble in chloroform, sparingly soluble
in alcohol and practically
insoluble in ether.
CLINICAL PARTICULARS
THERAPEUTIC INDICATIONS
Hypertension
POSOLOGY AND METHOD OF ADMINISTRATION
The doses of Isoptin
®
SR 240mg, individualized according to the severity of the disease, are
to be taken regularly as prescribed by the physician. The film
coated tablets are to be swallowed whole with some fluid, preferably
with or shortly after meals. Unless otherwise instructed, the daily
dose for adults is 1
film coated tablet in the morning (patients requiring particularly
gradual blood pressure lowering should be started on half tablet taken
in the morning). If
after about 2 weeks of treatment a dose increase is found to be
necessary the dose can be raised to a maximum of 2 film coated
tablets daily (additionally
1 half to 1 film coated tablet in the evening after an interval of
about 12 hours). On long-term treatment a daily dose of 480mg should
not be exceeded;
short-term dose increases are possible only when directed by the
physician. For children and adults requiring smaller doses