Isoflurane-Vet 100% w/w Inhalation Vapour, Liquid

Country: United Kingdom

Language: English

Source: VMD (Veterinary Medicines Directorate)

Active ingredient:

Isoflurane

Available from:

Boehringer Ingelheim Animal Health UK Ltd

ATC code:

QN01AB06

INN (International Name):

Isoflurane

Pharmaceutical form:

Inhalation vapour, liquid

Prescription type:

POM-V - Prescription Only Medicine – Veterinarian

Therapeutic group:

Cats, Dogs, Horses, Ornamental Birds

Therapeutic area:

Neurological Agent general anaesthetic

Authorization status:

Expired

Authorization date:

1996-11-15

Summary of Product characteristics

Revised: August 2019
AN: 00674/2019
Page 1 of 8
SUMMARY OF PRODUCT CHARACTERISTICS
1.
NAME OF THE VETERINARY MEDICINAL PRODUCT
ISOFLURANE-Vet 100% w/w Inhalation Vapour, Liquid
2.
QUALITATIVE AND QUANTITATIVE COMPOSITION
Isoflurane 100% w/w
3.
PHARMACEUTICAL FORM
Inhalation vapour, liquid.
For full list of excipients, see section 6.1
4.
CLINICAL PARTICULARS
4.1
TARGET SPECIES
Dogs, cats, horses and ornamental birds.
4.2
INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES
For the induction and maintenance of general anaesthesia in dogs,
cats,
horses and ornamental birds.
4.3
CONTRA-INDICATIONS
Do not use in animals with a known sensitivity to Isoflurane or other
inhalational agents.
4.4
SPECIAL WARNINGS FOR EACH TARGET SPECIES
When using Isoflurane to anaesthetise an animal with a head injury,
consideration
should
be
given
as
to
whether
artificial
ventilation
is
appropriate to maintain normal CO
2
levels, so that cerebral blood flow
does not increase.
In cats, intubation may be assisted by use of lidocaine spray to avoid
laryngospasm.
Revised: August 2019
AN: 00674/2019
Page 2 of 8
4.5
SPECIAL PRECAUTIONS FOR USE
(I) SPECIAL PRECAUTIONS FOR USE IN ANIMALS
Isoflurane produces a dose-related depression of respiration and, with
increasing depth of anaesthesia, both tidal volume and respiratory
rate
are
decreased.
This
depression
is
partially
reversed
by
surgical
stimulation even at deep levels of anaesthesia.
Respiratory
activity
should
be
monitored
closely
and
assisted
or
controlled when necessary.
Administration of Isoflurane will also produce a dose-related
depression
of arterial blood pressure, although this is raised by surgical
stimulation.
Any excessive depression of the arterial blood pressure, unrelated to
hypovolemia is normally related to the depth of anaesthesia. It can
usually be corrected by reducing the administered concentration of
Isoflurane although it may be necessary, in horses, to administer an
inotropic agent such as dobutamine. However, the heart rate is
normally stable and, by the use of contro