FUROQUID

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

FUROSEMIDE (UNII: 7LXU5N7ZO5) (FUROSEMIDE - UNII:7LXU5N7ZO5)

Available from:

Butler Animal health Supply, LLC dba Covetrus North America

INN (International Name):

FUROSEMIDE

Composition:

FUROSEMIDE 10 mg in 1 mL

Administration route:

ORAL

Prescription type:

PRESCRIPTION

Therapeutic indications:

DOG Furosemide Syrup 1% is an effective diuretic possessing a wide therapeutic range. Pharmacologically it promotes the rapid removal of abnormally retained extracellular fluids. The rationale for the efficacious use of diuretic therapy is determined by the clinical pathology producing the edema. Furosemide Syrup 1% is indicated for the treatment of edema (pulmonary congestion, ascites) associated with cardiac insufficiency and acute noninflammatory tissue edema. The continued USB of heart stimulants, such as digitalis or its glycosides, is indicated in cases of edema involving cardiac insufficiency. Furosemide Syrup 1% is a highly effective diuretic-saluretic which if given in excessive amounts may result in dehydration and electrolyte imbalance. Therefore, the dosage and schedule may have to be adjusted to the patients' needs. The animal should be observed for early signs of electrolyte imbalance, and corrective measures administered. Early signs of electrolyte imbalance are: Increased thirst, lethargy, dro

Product summary:

Furosemide Syrup 1% (10 mg/mL), available in 60 mL bottles with calibrated safety dropper.

Authorization status:

Abbreviated New Animal Drug Application

Summary of Product characteristics

FUROQUID 1%- FUROSEMIDE SYRUP
BUTLER ANIMAL HEALTH SUPPLY, LLC DBA COVETRUS NORTH AMERICA
----------
FUROQUID
(FUROSEMIDE) SYRUP 1%
(10 mg/mL)
WITH CALIBRATED SAFETY DROPPER
FOR USE IN DOGS ONLY
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
FOR ANIMAL USE ONLY
KEEP OUT OF REACH OF CHILDREN
ANADA 200-373, Approved by FDA
DESCRIPTION:
Furosemide Syrup 1% is a chemically distinct diuretic and saluretic
pharmacodynamically characterized
by the following:
1. A high degree of efficacy, low-inherent toxicity and a high
therapeutic index.
2. A rapid onset of action of comparatively short duration.
3. A pharmacologic action in the functional area of the nephron, i.e.,
proximal and distal tubules and the
ascending limb of the loop Henle.
4. A dose-response relationship and a ratio of minimum to maximum
effective dose range greater than
ten fold.
5. It is administered orally. It is readily absorbed from the
intestinal tract and well tolerated.
The CAS Registry Number is: 54-31-9.
This product contains alcohol 11.5% USP as a preservative, and FD&C
Yellow #6 and D&C Yellow
#10 as color additives.
Furosemide Syrup 1%, a diuretic, is an anthranilic acid derivative
with the following structural formula:
Generic name: Furosemide (except in United Kingdom-frusemide).
Chemical name: 4-chloro-N-
furfuryl-5-sulfamoylanthranilic acid.
1,2
2,4
1,2
ACTIONS
The therapeutic efficacy of Furosemide Syrup 1 % is from the activity
of the intact and unaltered
molecule throughout the nephron, inhibiting the reabsorption of sodium
not only in the proximal and
distal tubule, but also in the ascending limb of the loop of Henle.
The prompt onset of action is a result
of the drug's rapid absorption and a poor lipid solubility. The low
lipid solubility and a rapid renal
excretion minimizes the possibility of lipid accumulation in tissues
and organs or of crystalluria.
Furosemide Syrup 1 % has no inhibitory effect on carbonic anhydrase or
aldosterone activity in the
distal tubule. The drug possesses diu