FOSVET-T WATER SOLUBLE POWDER

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

FOSFOMYCIN CALCIUM; TYLOSIN TARTRATE

Available from:

Life Biopharma Sdn. Bhd.

INN (International Name):

FOSFOMYCIN CALCIUM; TYLOSIN TARTRATE

Units in package:

1 kg; 200 gm; 500 gm; 100 gm

Manufactured by:

Life Biopharma Sdn. Bhd.

Patient Information leaflet

FOR ANIMAL USE ONLY
BRAND OR PRODUCT NAME :
FOSVET-T Water Soluble Powder
NAME AND STRENGTH OF ACTIVE SUBSTANCE(S)
Each gram of FOSVET-T Water Soluble Powder contains Fosfomycin Calcium
200mg and Tylosin Tartrate 50mg.
PRODUCT DESCRIPTION
FOSVET-T Water Soluble Powder is a white or light milky white powder.
PHARMACODYNAMICS AND PHARMACOKINETICS PROPERTIES
Tylosin is a macrolide antibiotic produced by a strain of Streptomyces
fradiae. It exerts its antimicrobial effect by inhibiting protein
synthesis of susceptible micro-organisms. The
tylosin spectrum of activity includes Gram-positive bacteria including
Clostridium perfringens and some Gram-negative strains such as
Pasteurella and Mycoplasma spp. at
concentrations of 16µg/ml or less. Absorption: Tylosin reaches
maximal blood levels between 1 and 3 hours after an oral dose. Minimal
or no blood levels remain 24 hours after
an oral dose. Distribution: After oral doses were given to pigs,
tylosin was found in all tissues, between 30 minutes and two hours
after administration, except for the brain and
spinal cord. Biotransformation and Elimination: It has been shown that
most of the material which is excreted is to be found in the faeces
and consists of tylosin (factor A),
relomycin (factor D) and dihydrodesmycosin.
Fosfomycin is a phosphoenol pyruvate analog that irreversibly inhibits
pyruvyl transferase, the enzyme that catalyzing the first step of
peptidoglycan biosynethesis. Fosfomycin is
a broad-spectrum antibiotic produced by various Streptomyces spp. It
is effective against many Gram-positive and Gram-negative. It is
particularly active against many
Enterobacteriaceae, including E.coli and also is active against
Pasteurella, Salmonella, and Staphylococcus. After PO administration,
absorption of fosfomycin occurs throughout
the digestive tract. Fosfomycin has no metabolic transformation and is
excreted in active form mostly through renal elimination.
INDICATION
For use in poultry (broilers; light and heavy breeders) in the
treatment of bacterial infections cau

Summary of Product characteristics

FOR ANIMAL USE ONLY
BRAND OR PRODUCT NAME :
FOSVET-T Water Soluble Powder
NAME AND STRENGTH OF ACTIVE SUBSTANCE(S)
Each gram of FOSVET-T Water Soluble Powder contains Fosfomycin Calcium
200mg and Tylosin Tartrate 50mg.
PRODUCT DESCRIPTION
FOSVET-T Water Soluble Powder is a white or light milky white powder.
PHARMACODYNAMICS AND PHARMACOKINETICS PROPERTIES
Tylosin is a macrolide antibiotic produced by a strain of Streptomyces
fradiae. It exerts its antimicrobial effect by inhibiting protein
synthesis of susceptible micro-organisms. The
tylosin spectrum of activity includes Gram-positive bacteria including
Clostridium perfringens and some Gram-negative strains such as
Pasteurella and Mycoplasma spp. at
concentrations of 16µg/ml or less. Absorption: Tylosin reaches
maximal blood levels between 1 and 3 hours after an oral dose. Minimal
or no blood levels remain 24 hours after
an oral dose. Distribution: After oral doses were given to pigs,
tylosin was found in all tissues, between 30 minutes and two hours
after administration, except for the brain and
spinal cord. Biotransformation and Elimination: It has been shown that
most of the material which is excreted is to be found in the faeces
and consists of tylosin (factor A),
relomycin (factor D) and dihydrodesmycosin.
Fosfomycin is a phosphoenol pyruvate analog that irreversibly inhibits
pyruvyl transferase, the enzyme that catalyzing the first step of
peptidoglycan biosynethesis. Fosfomycin is
a broad-spectrum antibiotic produced by various Streptomyces spp. It
is effective against many Gram-positive and Gram-negative. It is
particularly active against many
Enterobacteriaceae, including E.coli and also is active against
Pasteurella, Salmonella, and Staphylococcus. After PO administration,
absorption of fosfomycin occurs throughout
the digestive tract. Fosfomycin has no metabolic transformation and is
excreted in active form mostly through renal elimination.
INDICATION
For use in poultry (broilers; light and heavy breeders) in the
treatment of bacterial infections cau