Country: Israel
Language: English
Source: Ministry of Health
TOCOPHEROL (VIT E) (AS TOCOPHERYL ACETATE)
TEVA PHARMACEUTICAL INDUSTRIES LTD, ISRAEL
A11HA03
TABLETS
TOCOPHEROL (VIT E) (AS TOCOPHERYL ACETATE) 200 MG
PER OS
Not required
TEVA PHARMACEUTICAL INDUSTRIES LTD, ISRAEL
TOCOPHEROL (VIT E)
TOCOPHEROL (VIT E)
For the prevention and treatment of diseases caused by Vitamin E deficiency.
2013-10-31
Evitol Tablets, 1 4. 2014, RH " ע עבקנ הז ןולע טמרופ " רשואו קדבנ ונכותו תואירבה דרשמ י ." רשואמ ןולע : 31/3/2014 “This leaflet form at has been determined by the Ministry of Health and the content thereof has been checked and approved.” Date of approval: 31/3/2014 EVITOL ® TABLETS COMPOSITION Each tablet contains: _Active Ingredient _ dl-alpha-Tocopherol acetate 100 mg or 200 mg (Vitamin E) _Other Ingredients _ Microcrystalline cellulose, silicon dioxide, hydrogenated vegetable oil, povidone, gelatin, sucrose * , maize starch, sodium alumino-silicate. * _Each Evitol 100 mg tablet contains 9.4 mg sucrose_. _* Each Evitol 100 mg tablet contains 1.74 mg sodium. _ _ _ _*_ _ Each Evitol 200 mg tablet contains 18.8 mg sucrose. _ _* Each Evitol 200 mg tablet contains 3.5 mg sodium. _ _ _ MECHANISM OF ACTION Vitamin E is a fat-soluble intracellular antioxidant. It plays an important role in preventing oxidation of essential cellular constituents, thereby preventing the formation of toxic oxidation products, such as the peroxides formed from unsaturated fatty acids. These lipid peroxides are known to damage cell membranes. Vitamin E deficiency plays a significant role in the pathogenesis of hemolytic anemia in premature infants. Its antioxidant property is important for the maintenance of red cell viability. It is also quite likely that vitamin E deficiency predisposes to the development of retrolental fibroplasia in premature infants exposed to higher oxygen tensions than those of the intrauterine environment. The need of the body for vitamin E is considerably increased by diets that contain foods rich in polyunsaturated fatty acids. This explains vitamin E deficiency in infants fed on formulas rich in such fatty acids. This deficiency is corrected by the administration of vitamin E. In fact, it has been shown that levels of vitamin E rise much slower in artificially-fed infants than in those who are breastfed. Human atheromatous lesions contain lipid peroxides. F Read the complete document