ENGEMYCIN

Country: New Zealand

Language: English

Source: Ministry for Primary Industries

Active ingredient:

oxytetracycline

Available from:

Schering-Plough Animal Health Limited

INN (International Name):

oxytetracycline

Composition:

oxytetracycline 100 g/litre

Therapeutic area:

Antibiotic

Authorization status:

ACVM Registered

Authorization date:

1977-06-02

Patient Information leaflet

ENGEMYCIN
Leaflet, Carton and Label
A003308 Jan 2019
Page 1 of 6
ENGEMYCIN
Jan-2019
Leaflet
RESTRICTED VETERINARY MEDICINE
Keep out of reach of children
FOR ANIMAL TREATMENT ONLY
ENGEMYCIN
®
INJECTABLE AQUEOUS SOLUTION OF OXYTETRACYCLINE
READ ENTIRE LEAFLET BEFORE USE.
DESCRIPTION
A patented, injectable aqueous solution of oxytetracycline as a
complex with magnesium and
polyvinyl pyrrolidone containing 100mg oxytetracycline (as the
hydrochloride) per mL.
PROPERTIES
Oxytetracycline is a broad-spectrum antibiotic with a primarily
bacteriostatic effect against
numerous Gram-positive and Gram-negative bacteria, rickettsia,
mycoplasma and chlamydia. The
formulation of Engemycin ensures that it is well tolerated at the site
of injection.
INDICATIONS
The treatment of infections caused by microorganisms sensitive to
oxytetracycline in horses,
cattle, sheep and pigs. Examples include infections occurring in cases
of pneumonia and other
respiratory tract infections, (endo) metritis, mastitis, urinary tract
infections, septicaemia and
secondary infections associated with viral diseases.
DOSAGE AND ADMINISTRATION
Engemycin can be administered either at a dose rate of 3-10 mg/kg
(depending on species and
age) for a shorter duration of activity (SA), or at a dose rate of
10-20 mg/kg (depending on
species and age) for a prolonged duration of activity (PA). SA effect
provides a duration of action
of 24 hours following a single injection while PA effect provides a
duration of action of 48 hours
following a single injection. This latter scheme should not be used
for intravenous injections.
THE SHORT ACTING (REPEAT) DOSE IS GIVEN AT 24-HOUR INTERVALS UP TO A
MAXIMUM OF 5 DOSES IN
TOTAL. THE PROLONGED ACTION DOSE IS GIVEN AT 48-HOUR INTERVALS, UP TO
A MAXIMUM OF 2 DOSES
IN TOTAL.
SHORTER ACTION EFFECT
Species
Route
mg/kg
Weight
(kg)
Dose
(mLs)
Cow
i.v./i.m.
3-5
500
15-25
Calf
i.v./i.m.
8
100
8
Horse
i.v./i.m.
5
500
25
Foal
i.v./i.m.
10
100
10
Pig
i.m.
5
50
2.5
Piglet
i.m.
8
5
0.4
Sheep
i.v./i.m.
8
50
4
ENGEMYCIN
Leaflet, Carton and

Summary of Product characteristics

ENGEMYCIN
100 mL and 250 mL – Leaflet, Carton and Label
A003308
Page 1 of 6
ENGEMYCIN
11-Oct-21
Leaflet
RESTRICTED VETERINARY MEDICINE
KEEP OUT OF REACH OF CHILDREN
FOR ANIMAL TREATMENT ONLY
ENGEMYCIN
®
INJECTABLE AQUEOUS SOLUTION OF OXYTETRACYCLINE
READ ENTIRE LEAFLET BEFORE USE.
DESCRIPTION
A patented, injectable aqueous solution of oxytetracycline as a
complex with magnesium and
polyvinyl pyrrolidone containing 100 mg oxytetracycline (as the
hydrochloride) per mL.
PROPERTIES
Oxytetracycline is a broad-spectrum antibiotic with a primarily
bacteriostatic effect against
numerous Gram-positive and Gram-negative bacteria, rickettsia,
mycoplasma and chlamydia. The
formulation of Engemycin ensures that it is well tolerated at the site
of injection.
INDICATIONS
The treatment of infections caused by microorganisms sensitive to
oxytetracycline in horses,
cattle, sheep and pigs. Examples include pneumonia and other
respiratory tract infections, urinary
tract infections, septicaemia and secondary infections associated with
viral diseases.
DOSAGE AND ADMINISTRATION
Engemycin can be administered either at a dose rate of 3-10 mg/kg
(depending on species and
age) for a shorter duration of activity (SA), or at a dose rate of
10-20 mg/kg (depending on
species and age) for a prolonged duration of activity (PA). SA effect
provides a duration of action
of 24 hours following a single injection while PA effect provides a
duration of action of 48 hours
following a single injection. This latter scheme should not be used
for intravenous injections.
THE SHORT ACTING (REPEAT) DOSE IS GIVEN AT 24-HOUR INTERVALS UP TO A
MAXIMUM OF 5 DOSES IN
TOTAL. THE PROLONGED ACTION DOSE IS GIVEN AT 48-HOUR INTERVALS, UP TO
A MAXIMUM OF 2 DOSES
IN TOTAL.
Not for use in bobby calves.
In food producing animals, the injection is to be given into the
anterior half of the neck.
Intravenous injections should be given slowly over a period of at
least one minute. Normal aseptic
precautions should always be taken. Injections may be repeated as
required. Repea