DYNORMIN TABLET 50MG

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

ATENOLOL

Available from:

DYNAPHARM (M) SDN BHD

INN (International Name):

ATENOLOL

Units in package:

100 Tablets; 500 Tablets

Manufactured by:

DYNAPHARM (M) SDN BHD

Patient Information leaflet

_Consumer Medication Information Leaflet (RiMUP) _
DYNORMIN TABLET 50MG
1
Atenolol (50mg)
What is in this leaflet
1.
What Dynormin Tablet 50mg is used for
2.
How Dynormin Tablet 50mg works
3.
Before you take Dynormin Tablet 50mg
4.
How to take Dynormin Tablet 50mg
5.
While you are using Dynormin Tablet
50mg
6.
Side effects
7.
Storage and disposal of Dynormin
Tablet 50mg
8.
Product description
9.
Manufacturer and product registration
holder
10.
Date of revision
WHAT DYNORMIN TABLET 50MG IS USED
FOR
Dynormin Tablet 50mg contains the active
ingredient atenolol. It belongs to a group of
medicines called beta-blockers.
It is used to:
-
Control high blood pressure.
-
Relieve chest pain (angina pectoris).
-
Control irregular heart beat.
-
Protect the heart in the early treatment
after a heart attack.
HOW DYNORMIN TABLET 50MG WORKS
Dynormin Tablet 50mg works by slowing
down the heart and reducing its workload.
BEFORE YOU TAKE DYNORMIN TABLET 50MG
_When you must not use it _
Do not take Dynormin Tablet 50mg and
tell your doctor if you:
-
Are allergic (hypersensitive) to atenolol
or any of the other ingredients in
Dynormin Tablet 50mg – refer section 8.
-
Have second or third degree heart block.
-
Have shock caused by heart problems.
-
Have heart failure which is not under
control.
-
Suffer with heart conduction or
rhythm problems
-
Have a slow heart rate
-
Have low blood pressure.
-
Suffer from an increased acidity of
the blood (metabolic acidosis)
-
Have or have had breathing problems
such as asthma, difficulty breathing due
to narrowing of the airways or reversible
obstructive airways disease. Do not take
this medicine if you have a history of
wheezing or asthma. Consult your doctor
or pharmacist first.
_Before you start to use it _
Take special care with Dynormin Tablet
50mg and tell your doctor if you:
-
Have a history of allergic reactions
-
Have heart problems such as heart
failure, untreated congestive heart failure,
ischaemic heart disease, poor heart
function (poor cardiac reserve) or first
degree heart block.

Summary of Product characteristics

DYNORMIN
DESCRIPTION
CONTENT
DYNORMIN TABLET 50MG
MAL19971838AZ
TABLET
Colour
:
White
Shape
:
Round, Biconvex and Scored
Coating
:
Film-coated
Each Tablet Contains:
Atenolol ........................ 50 mg
DYNORMIN TABLET 100MG
MAL19913259AZ
TABLET
Colour
:
Orange
Shape
:
Round, Biconvex and Scored
Marking :
“D”
Coating
:
Film-coated
Each Tablet Contains:
Atenolol ...................... 100 mg
PHARMACODYNAMICS:
Atenolol is a

-adrenoceptor blocking agent which is cardioselective (i.e. acts
preferentially on

-adrenergic receptors in the
heart). It is without intrinsic sympathomimetic and membrane
stabilising activities. It crosses the blood brain barrier only to a
negligible extent. Atenolol is effective for at least 24 hours after a
single oral dose.
PHARMACOKINETICS:
Atenolol appears to be incompletely absorbed from the gastrointestinal
tract and is not significantly metabolised. It is excreted
in the urine and its biological half-life is longer than would be
anticipated from its plasma half-life of about 6 to 7 hours.
Atenolol diffuses across the placenta and is excreted in the breast
milk. Only small amounts are reported to cross the blood-
brain-barrier, and it is only about 5% bound to plasma proteins.
INDICATION:
Control of hypertension. Management of angina pectoris and cardiac
dysrhythmias. Prophylaxis of myocardial infraction.
RECOMMENDED DOSE:
Hypertension: Most patients reported to 50 - 100 mg daily given orally
as a single dose. The effect will be fully established after
one to two week.
Angina: Most patients with angina pectoris will respond to 100 mg
daily given orally as a single or divided dose. It is unlikely that
additional benefit will be gained by increasing the dose.
Dysrhythmias: Having controlled the dysrhythmias with intravenous
administration of Atenolol, a suitable oral maintenance
dosage is 50 - 100 mg daily, given as a single dose.
Myocardial Infarction: Treatment should be given within 12 hours of
the onset of chest pain: 5 to 10 mg should be given by I.V.
injection and foll