Dopram V Injection 20 mg/ml Solution for Injection

Country: United Kingdom

Language: English

Source: VMD (Veterinary Medicines Directorate)

Active ingredient:

Doxapram Hydrochloride

Available from:

Zoetis UK Limited

ATC code:

QR07AB01

INN (International Name):

Doxapram Hydrochloride

Pharmaceutical form:

Solution for injection

Prescription type:

POM-V - Prescription Only Medicine – Veterinarian

Therapeutic group:

Cats, Cattle, Dogs, Horses, Sheep

Therapeutic area:

Respiratory stimulant

Authorization status:

Expired

Authorization date:

1994-09-07

Summary of Product characteristics

Revised: January 2014
AN: 01221/2013
Page 1 of 6
SUMMARY OF PRODUCT CHARACTERISTICS
1.
NAME OF THE VETERINARY MEDICINAL PRODUCT
Dopram
V Injection 20 mg/ml Solution for Injection
2.
QUALITATIVE AND QUANTITATIVE COMPOSITION
ACTIVE SUBSTANCES:
Each 1ml contains:
Doxapram Hydrochloride
20.0 mg (equivalent to 17.5mg doxapram)
EXCIPIENT(S):
Chlorbutanol
5.0 mg as antimicrobial preservative
For a full list of excipients, see section 6.1.
3.
PHARMACEUTICAL FORM
Solution for injection or sublingual administration.
A clear colourless solution.
4.
CLINICAL PARTICULARS
4.1
TARGET SPECIES
Dogs, cats, horses, calves and lambs.
4.2
INDICATIONS FOR USE, SPECIFYING THE TARGET SPECIES
_RESPIRATORY STIMULANT_
_For dogs, cats and horses:_
1. To stimulate respiration during and after general anaesthesia.
2. To speed awakening and return of reflexes after anaesthesia, when
this
is considered beneficial.
_Neonate dogs, cats, calves and lambs:_
1. To initiate respiration following dystocia or Caesarean section.
2. To stimulate respiration following dystocia or Caesarean section.
4.3
CONTRAINDICATIONS
None.
Revised: January 2014
AN: 01221/2013
Page 2 of 6
4.4
SPECIAL WARNINGS FOR EACH TARGET SPECIES
Special warnings include use in dogs which have been sedated with
morphine
(see 4.5).
Not to be used in known cases of epilepsy, cardiac dysfunction,
hyperthyroidism
or severe hepatic impairment.
4.5
SPECIAL PRECAUTIONS FOR USE
i. Special precautions for use in animals
Dosage should be adjusted to meet the requirements of the situation.
Adequate,
but not excessive, doses should be used. A patent airway is essential.
Reflexes
should be checked periodically.
Excessive doses may produce hyperventilation which may be followed by
reduced carbon dioxide tension in the blood, cerebral
vasoconstriction, hypoxia,
and possible brain damage.
Excessive doses administered to animals, during or following
anaesthesia with
cyclopropane or halogenated hydrocarbon anaesthetics, may precipitate
cardiac
arrhythmias.
The product should be used with extreme cauti