Dopamine 200mg/5ml solution for infusion ampoules

Country: United Kingdom

Language: English

Source: MHRA (Medicines & Healthcare Products Regulatory Agency)

Active ingredient:

Dopamine hydrochloride

Available from:

Martindale Pharmaceuticals Ltd

ATC code:

C01CA04

INN (International Name):

Dopamine hydrochloride

Dosage:

40mg/1ml

Pharmaceutical form:

Solution for infusion

Administration route:

Intravenous

Class:

No Controlled Drug Status

Prescription type:

Valid as a prescribable product

Product summary:

BNF: 02070100; GTIN: 5014124170780

Patient Information leaflet

IN THIS LEAFLET:
1.
What Dopamine Concentrate is and what it is used for
2.
Before you are given Dopamine Concentrate
3.
How Dopamine Concentrate is given
4.
Possible side effects
5.
Storing Dopamine Concentrate
6.
Further information
1. WHAT DOPAMINE CONCENTRATE IS AND WHAT IT
IS USED FOR
Dopamine hydrochloride is one of a group of medicines that
stimulate the heart and acts on blood vessels and the kidneys.
Dopamine Concentrate is used in the treatment of diseases of the
heart muscle, kidney failure and poor blood flow. It is also used
in the treatment of shock associated with heart attacks, trauma
(injury), blood poisoning, open heart surgery and heart failure.
2. BEFORE YOU ARE GIVEN DOPAMINE CONCENTRATE
YOU SHOULD NOT BE GIVEN DOPAMINE CONCENTRATE IF:
• you are allergic to Dopamine Hydrochloride or any of
ingredients listed in section 6 of this leaflet
• you have a tumour in the adrenal glands known as
phaeochromocytoma
• you have a fast and irregular heartbeat
TAKE SPECIAL CARE WITH DOPAMINE CONCENTRATE IF:
• you are pregnant or breast-feeding.
If any of the above applies to you, please consult your doctor
before you are given Dopamine Concentrate.
TAKING WITH OTHER MEDICINES
Please tell your doctor or nurse if you are taking or have recently
taken any other medicines, including those obtained without
prescription.
Medicines that may interact with Dopamine Concentrate include:
• medicines used to treat depression such as amitriptyline
• phenytoin, a medicine used to treat fits
• dopexamine, a medicine used to increase blood flow
• ergotamine, a medicine used to treat headaches
• guanethidine, a medicine used to treat high blood pressure
• adrenergic blocking agents such as doxazosin
• Monoamine-Oxidase Inhibitors (MAOI), a type of medicine
used to treat depression
• certain anaesthetics, such as halothane
• entacapone, a medicine used in Parkinson’s disease
• doxapram, used as a respiratory stimulant.
IF YOU HAVE ANY DOUBTS ABOUT WHETHER THIS MEDICINE SHOULD
BE ADMINISTERED TO

Summary of Product characteristics

OBJECT 1
STERILE DOPAMINE CONCENTRATE BP 200MG/5ML
Summary of Product Characteristics Updated 26-Sep-2014 | Martindale
Pharma
1. Name of the medicinal product
Sterile Dopamine Concentrate BP 200mg/5ml
2. Qualitative and quantitative composition
Dopamine Hydrochloride BP 40mg/ml
3. Pharmaceutical form
Solution for injection
4. Clinical particulars
4.1 Therapeutic indications
Dopamine hydrochloride is used for the correction of poor perfusion,
low cardiac output, impending renal
failure and shock associated with myocardial infarction, trauma,
endotoxic septicaemia, open heart
surgery and heart failure.
4.2 Posology and method of administration
Preparation
The normal usage is a concentration of 1,600mcg/ml of dopamine
hydrochloride in an infusion fluid. This
may be prepared by aseptically transferring solution equivalent to
800mg of dopamine hydrochloride into
500ml of one of the following sterile intravenous solutions.
Sodium chloride intravenous infusion BP
Sodium chloride and dextrose intravenous infusion BP
5% dextrose intravenous infusion BP
5% dextrose in compound sodium lactate intravenous infusion BP
Compound sodium lactate intravenous infusion BP (Hartmann's Lactate
Ringer)
Dilution should be made just before administration, if possible.
However, the infusion dilutions are stable
for at least 24 hours if necessary.
NB. DO NOT ADD DOPAMINE HYDROCHLORIDE TO SODIUM BICARBONATE OR OTHER
ALKALINE SOLUTION AS DRUG
DECOMPOSITION WILL OCCUR.
Dosage and administration
After dilution, dopamine should be administered through an intravenous
catheter or needle in as large a
vein as possible. It is essential to use a IV drop chamber or infusion
pump so that the rate of infusion may
be controlled in drops (ml) per minute. The infusion rate should be
adjusted according to the patients
condition. Where appropriate, restoration of the blood volume with a
suitable plasma expander should
take place before dopamine therapy.
In patients likely to respond to modest increments in heart force and
renal perfusion, begin dopamine
inf