CYDECTIN- moxidectin injection, solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

moxidectin (UNII: NGU5H31YO9) (moxidectin - UNII:NGU5H31YO9)

Available from:

Elanco US Inc.

Administration route:

SUBCUTANEOUS

Prescription type:

OTC

Therapeutic indications:

CYDECTIN Injectable, when administered at the recommended dose level of 0.2 mg/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle: Gastrointestinal Roundworms Lungworms Ostertagia ostertagi - Adults and L4 (including inhibited Larvae)   Dictyocaulus viviparus - Adults and L4 Haemonchus placei - Adults Cattle Grubs Trichostrongylus axei - Adults and L4   Hypoderma bovis Trichostrongylus colubriformis - Adults and L4   Hypoderma lineatum Cooperia oncophora - Adults Mites Cooperia pectinata - Adults   Psoroptes ovis Cooperia punctata - Adults and L4   (Psoroptes communis var. bovis) Cooperia spatulata - Adults Lice Cooperia surnabada - Adults and L4   Linognathus vituli Nematodirus helvetianus - Adults   Solenopotes capillatus Oesophagostomum radiatum - Adults and L4 Trichuris spp. - Adults Persistent Activity: CYDECTIN Injectable has been proven to effectively protect cattle from reinfection with Dictyocaulus viviparus and Oesophagostomum radiatum for 42 days after treatment, Haemonchus placei for 35 days after treatment, and Ostertagia ostertagi and Trichostrongylus axei for 14 days after treatment. Management Considerations for External Parasites: For most effective external parasite control, CYDECTIN Injectable should be administered to all cattle in the herd. Cattle entering the herd following this administration should be treated prior to introduction. Consult your veterinarian or a livestock entomologist for the most appropriate time to administer CYDECTIN Injectable in your location to effectively control external parasites.

Authorization status:

New Animal Drug Application

Summary of Product characteristics

CYDECTIN- MOXIDECTIN INJECTION, SOLUTION
ELANCO US INC.
----------
Approved by FDA under NADA # 141-220.
CYDECTIN
moxidectin
INJECTABLE SOLUTION FOR BEEF AND NONLACTATING DAIRY CATTLE
Antiparasitic
Contains 10 mg moxidectin/mL
NOT FOR USE IN FEMALE DAIRY CATTLE 20 MONTHS OF AGE OR OLDER
(INCLUDING DRY
DAIRY COWS), VEAL CALVES, AND CALVES LESS THAN 8 WEEKS OF AGE.
FOR TREATMENT OF INFECTIONS AND INFESTATIONS DUE TO INTERNAL AND
EXTERNAL
PARASITES OF CATTLE
Consult your veterinarian for assistance in the diagnosis, treatment
and control of
parasitism.
PRODUCT DESCRIPTION
CYDECTIN Injectable Solution is a ready-to-use, sterile solution
containing 1%
moxidectin. Moxidectin is an endectocide in the milbemycin chemical
class which shares
the distinctive mode of action characteristic of macrocyclic lactones.
CYDECTIN
Injectable is specially formulated to allow moxidectin to be absorbed
from the site of
injection and distributed internally to the areas of the body affected
by endo- and/or
ectoparasitism. Moxidectin binds selectively and with high affinity to
glutamate-gated
chloride ion channels which are critical to the function of
invertebrate nerve and muscle
cells. This interferes with neurotransmission resulting in paralysis
and elimination of the
parasite.
INDICATIONS
CYDECTIN Injectable, when administered at the recommended dose level
of 0.2 mg/2.2
lb (0.2 mg/kg) body weight, is effective in the treatment and control
of the following
internal and external parasites of cattle:
GASTROINTESTINAL ROUNDWORMS
LUNGWORMS
_Ostertagia ostertagi_ - Adults and L (including inhibited
Larvae)
_ Dictyocaulus viviparus_ - Adults
and L
_Haemonchus placei_ - Adults
CATTLE GRUBS
_Trichostrongylus axei_ - Adults and L
_ Hypoderma bovis_
_Trichostrongylus colubriformis_ - Adults and L
_ Hypoderma lineatum_
_Cooperia oncophora_ - Adults
MITES
_Cooperia pectinata_ - Adults
_ Psoroptes ovis_
TM
4
4
4
4
_Cooperia punctata_ - Adults and L
_ (Psoroptes communis_ var.
_bovis)_
_Cooperia spatulata_ - Adults
LICE
_Cooperia surnabada_ - Adults