CURAM DUO and CURAM DUO FORTE tablets

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

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Active ingredient:

Potassium clavulanate; Amoxicillin trihydrate; Amoxycilin trihydrate

Available from:

Sandoz Pty Ltd

Class:

Medicine Registered

Summary of Product characteristics

                                _Product Information _
_ _
_Page 1 _
_Amoxycillin/Clavulanic acid _
_August 2012 _
 
_________________________________________________________________________________ 
_Sandoz Pty Ltd_ 
 
 
PRODUCT INFORMATION 
CURAM
®
 DUO 500/125 AND CURAM
®
 DUO FORTE 875/125 TABLETS 
 
 
NAME OF THE MEDICINE 
 
Curam Duo 500/125 and Curam Duo Forte 875/125 tablet preparations are
a combination 
products containing amoxycillin trihydrate
and potassium clavulanate. 
 
_Chemical Name: _
 
Amoxycillin trihydrate 
_(_2_S,_5_R,_6_R)_-6-[(_R_)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-
azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate 
 
Potassium clavulanate 
Potassium (_Z_)-(2_R_, 5_R_)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-
azabicyclo[3.2.0]heptane-2-carboxylate 
 
_Structural Formula: _
 
Amoxycillin trihydrate 
 
Potassium clavulanate 
 
 
_Molecular Formula:  _
Amoxycillin Trihydrate   
C
16
H
19
N
3
O
5
S, 3H
2
O 
Potassium Clavulanate  
C
8
H
8
KNO
5
 
 
_Molecular Weight: _
Amoxycillin Trihydrate   
419.4 
Potassium Clavulanate  
237.3 
 
_CAS Number: _
Amoxycillin Trihydrate   
61336-70-7 
Potassium Clavulanate  
61177-45-5 
_Product Information _
_ _
_Page 2 _
_Amoxycillin/Clavulanic acid _
_August 2012 _
 
_________________________________________________________________________________ 
_Sandoz Pty Ltd_ 
 
DESCRIPTION 
 
Amoxycillin trihydrate is white
to almost white, crystalline powder, slightly soluble
in water 
and in alcohol, practically insoluble
in ether and in fatty oils. It dissolves in dilute acids
and 
dilute solutions of alkali hydroxides. 
 
Potassium clavulanate is white to
almost white, crystalline powder, hygroscopic, freely 
soluble in water, slightly soluble in alcohol, and
very slightly soluble in acetone. 
 
Each tablet contains the following ingredients: 
 
_Active Ingredients: _
 
 
Amoxycillin  
                                
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