Clinimix N14G30E infusion 2litre bags

Country: United Kingdom

Language: English

Source: MHRA (Medicines & Healthcare Products Regulatory Agency)

Active ingredient:

L-Phenylalanine; L-Lysine; L-Isoleucine; L-Valine; L-Histidine; L-Threonine; Tryptophan; L-Alanine; L-Arginine; Glycine; L-Proline; L-Leucine; L-Serine; L-Tyrosine; Sodium acetate trihydrate; Dipotassium hydrogen phosphate; Sodium chloride; Magnesium chloride hexahydrate; Glucose monohydrate; Calcium chloride dihydrate; L-Methionine

Available from:

Baxter Healthcare Ltd

ATC code:

B05XA07

INN (International Name):

L-Phenylalanine; L-Lysine; L-Isoleucine; L-Valine; L-Histidine; L-Threonine; Tryptophan; L-Alanine; L-Arginine; Glycine; L-Proline; L-Leucine; L-Serine; L-Tyrosine; Sodium acetate trihydrate; Dipotassium hydrogen phosphate; Sodium chloride; Magnesium chloride hexahydrate; Glucose monohydrate; Calcium chloride dihydrate; L-Methionine

Dosage:

2.38gram/1litre ; 2.47gram/1litre ; 2.55gram/1litre ; 2.47gram/1litre ; 2.04gram/1litre ; 1.79gram/1litre ; 770mg/1litre ; 8.8gram/1litre ; 4.89gram/1litre ; 4.38gram/1litre ; 2.89gram/1litre ; 3.1gram/1litre ; 2.13gram/1litre ; 170mg/1litre ; 2.97gram/1litre ; 2.61gram/1litre ; 770mg/1litre ; 510mg/1litre ; 165gram/1litre ; 330mg/1litre ; 1.7gram/1litre

Pharmaceutical form:

Infusion

Administration route:

Intravenous

Class:

No Controlled Drug Status

Prescription type:

Never Valid To Prescribe As A VMP

Product summary:

BNF: 09030000; GTIN: 55413760019678 05413760019673

Summary of Product characteristics

OBJECT 1
CLINIMIX N14G30E, SOLUTION FOR INFUSION
Summary of Product Characteristics Updated 13-Nov-2015 | Baxter
Healthcare Ltd
1. Name of the medicinal product
CLINIMIX N14G30E, solution for infusion
2. Qualitative and quantitative composition
CLINIMIX N14G30E is packaged in a dual compartment plastic bag
containing respectively an amino
acid solution with electrolytes and a glucose solution with calcium.
The injectable amino acid solution contains 15 L-amino acids (8
essential amino acids) needed for the
protein synthesis.
The amino acid profile is the following:
Essential amino acids/Total amino acids = 41.3 %
Essential amino acids/Total nitrogen = 2.83
Branched chain amino acids/Total amino acids = 19 %
The quantitative composition of CLINIMIX N14G30E is the following:
8.5% Amino acid solution with
electrolytes
30% Glucose solution with
calcium
Active ingredients
L-Leucine
6.20 g/l
L-Phenylalanine
4.76 g/l
L-Methionine
3.40 g/l
L-Lysine
4.93 g/l
(as L-Lysine hydrochloride)
(6.16 g/l)
L-Isoleucine
5.10 g/l
L-Valine
4.93 g/l
L-Histidine
4.08 g/l
L-Threonine
3.57 g/l
L-Tryptophan
1.53 g/l
L-Alanine
17.6 g/l
L-Arginine
9.78 g/l
Glycine
8.76 g/l
L-Proline
5.78 g/l
L-Serine
4.25 g/l
L-Tyrosine
0.34 g/l
Sodium acetate, 3H
2
O
5.94 g/l
Dibasic potassium phosphate
5.22 g/l
Sodium chloride
1.54 g/l
Magnesium chloride, 6H
2
O
1.02 g/l
Glucose
300 g/l
(as monohydrate glucose)
(330 g/l)
Calcium chloride, 2H
2
O
0.66 g/l
For the full list of excipients, see section 6.1
After mixing of the contents of both compartments, the composition of
the binary mixture, for all the
available bag sizes, is the following:
N14G30E
1 l
N14G30E
1.5 l
N14G30E
2 l
Nitrogen (g)
7.0
10.5
14.0
Amino acids (g)
43
64
85
Glucose (g)
150
225
300
Total calories (kcal)
770
1155
1540
Glucose calories (kcal)
600
900
1200
Sodium (mmol)
35
53
70
Potassium (mmol)
30
45
60
Magnesium (mmol)
2.5
3.8
5.0
Calcium (mmol)
2.3
3.4
4.5
Acetate (mmol)
70
105
140
Chloride (mmol)
40
60
80
Phosphate as HPO
4
2-
(mmol)
15
23
30
pH
6
Osmolarity (mOsm/l)
1415
3. Pharmaceu