Country: South Africa
Language: English
Source: South African Health Products Regulatory Authority (SAHPRA)
Roussel
CIDOMYCIN 20 mg INJECTION CIDOMYCIN 40 mg INJECTION CIDOMYCIN 80 mg INJECTION SCHEDULING STATUS: S4 PROPRIETARY NAME (and dosage form) CIDOMYCIN 20 mg INJECTION CIDOMYCIN 40 mg INJECTION CIDOMYCIN 80 mg INJECTION COMPOSITION gentamicin (as sulphate) 80 mg per 2 mL ampoule or vial paediatric - 20 mg per 2 mL ampoule or vial 40 mg per 1 mL ampoule or vial Preservatives: disodium edetate 0,01% m/v methyl hydroxybenzoate 0,18% m/v for 40 mg and 80 mg injection; 0,13% m/v for 20 mg injection propyl hydroxybenzoate 0,02% m/v PHARMACOLOGICAL CLASSIFICATION A. 20.1.1 broad and medium spectrum antibiotics. PHARMACOLOGICAL ACTION Cidomycin is a potent bactericidal antibiotic with a wide range of activity against both Gram-positive and Gram- negative organisms. Pseudomonas and Proteus organisms are in the main particularly susceptible to the action of cidomycin as also are strains of Staphylococcus resistant to other antibiotics. INDICATIONS Cidomycin injectable and cidomycin injectable (paediatric) are indicated in the treatment of systemic infections due to sensitive organisms. Urinary Tract Infections: Here, cidomycin's activity against some of the troublesome, generally resistant Gram-negative bacilli is invaluable. Especially to be mentioned are Pseudomonas and Proteus spp. which are often difficult to eradicate. Chest Infections: Especially in those conditions in which the causative organism is Gram-negative or resistant to other antibiotics. Septicaemias: Cidomycin is indicated in those cases of septicaemia due to organisms resistant to other antibiotics. Pseudomonas septicaemia has been treated successfully with gentamicin. Infected Burns: Where the most serious invading organisms, Pseudomonas and Staphylococcus spp., are both covered by the bactericidal activity of cidomycin. Empyema, Perito Read the complete document