Chronogest CR, 20 mg Controlled Release Vaginal Sponge for Sheep

Country: United Kingdom

Language: English

Source: VMD (Veterinary Medicines Directorate)

Active ingredient:

Flugestone Acetate

Available from:

MSD Animal Health UK Limited

ATC code:

QG03D

INN (International Name):

Flugestone Acetate

Pharmaceutical form:

Vaginal sponge

Prescription type:

POM-V - Prescription Only Medicine – Veterinarian

Therapeutic group:

Sheep

Therapeutic area:

Hormone sex

Authorization status:

Authorized

Authorization date:

2005-06-21

Summary of Product characteristics

Revised: January 2024
AN: 00003/2023
Page 1 of 5
SUMMARY OF PRODUCT CHARACTERISTICS
1.
NAME OF THE VETERINARY MEDICINAL PRODUCT
Chronogest CR 20mg controlled release vaginal sponge for sheep
2.
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each sponge contains:
ACTIVE SUBSTANCE:
17,9 mg flugestone equivalent to 20 mg flugestone acetate.
EXCIPIENTS:
QUALITATIVE COMPOSITION OF EXCIPIENTS
AND OTHER CONSTITUENTS
QUANTITATIVE COMPOSITION IF THAT
INFORMATION IS ESSENTIAL FOR PROPER
ADMINISTRATION OF THE VETERINARY
MEDICINAL PRODUCt
Hydroxypropylcellulose
20 mg
Macrogol 4000
20 mg
White cylindrical polyester polyurethane medicated sponge equipped
with string.
3.
CLINICAL INFORMATION
3.1
TARGET SPECIES
Sheep (ewe and ewelamb).
3.2
INDICATIONS FOR USE FOR EACH TARGET SPECIES
In
ewes
and
ewe
lambs,
in
combination
with
PMSG
(Pregnant
Mare
Serum
Gonadotropin)
-
Induction and synchronization of oestrus and ovulation (non cycling
ewes during
seasonal anoestrus and ewe lambs).
-
Synchronization of oestrus and ovulation (cycling ewes and ewe-lambs).
3.3
CONTRAINDICATIONS
None.
3.4
SPECIAL WARNINGS
None.
Revised: January 2024
AN: 00003/2023
Page 2 of 5
3.5
SPECIAL PRECAUTIONS FOR USE
Special precautions for safe use in the target species:
-
The repeated treatment with the product combined with PMSG may trigger
the
appearance of PMSG antibodies in some ewes. This in turn may affect
the time
of ovulation and result in reduced fertility when combined with fixed
time
artificial insemination at 55h following sponge removal.
-
The repeated use of sponges within one year has not been studied.
-
The
use
of
a
vaginal
applicator
designed
for
ewes
or
ewe
lambs
is
recommended to correctly insert sponges and to avoid vaginal injuries.
Special precautions to be taken by the person administering the
veterinary medicinal
product to animals:
Personal protective equipment consisting of single use gloves should
be worn when
handling the veterinary medicinal product.
The veterinary medicinal product should not be administered by
pregnant women or
women s