Chemmart Alprazolam

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Alprazolam

Available from:

Apotex Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

CHEMMART ALPRAZOLAM

_contains the active ingredient, alprazolam (al-PRAZ-oh-lam)_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
This leaflet answers some common
questions about alprazolam. It does
not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
THE INFORMATION IN THIS LEAFLET WAS
LAST UPDATED ON THE DATE LISTED ON
THE LAST PAGE.  MORE RECENT
INFORMATION ON THIS MEDICINE MAY
BE AVAILABLE.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
You can also download the most up
to date leaflet from
www.apotex.com.au.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits he/she expects it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
KEEP THIS LEAFLET WITH YOUR
MEDICINE. YOU MAY WANT TO READ IT
AGAIN.
WHAT ALPRAZOLAM IS
USED FOR
The name of your medicine is
Chemmart Alprazolam. It contains
the active ingredient alprazolam.
It is used to treat:
•
anxiety
•
panic attacks.
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed this
medicine for another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS_
Alprazolam belongs to a group of
medicines called benzodiazepines.
They are thought to work by their
action on brain chemicals.
In general, benzodiazepines such as
alprazolam should be taken for short
periods only (for example, 2 to 4
weeks). Continuous long-term use is
not recommended unless advised by
your doctor. The use of
benzodiazepines may lead to
dependence on the medicine.
_USE IN CHILDREN_
This medicine should not be used in
children.
BEFORE YOU TAKE
ALPRAZOLAM
_WHEN YOU MUST NOT TAKE IT_
DO NOT TAKE T

Summary of Product characteristics

Product Information – Australia

Chemmart Alprazolam Tablets 
Page 1 
CHEMMART ALPRAZOLAM TABLETS 

NAME OF THE MEDICINE  
Alprazolam. 

DESCRIPTION 
Alprazolam is a white crystalline powder, soluble in
methanol or ethanol but with no appreciable solubility 
in water. 

Chemical Name: 
8-chloro-1-methyl-6-phenyl-4H-s triazolo[4,3-alpha][1,4]benzodiazepine. 

Chemical Structure: 

Molecular Formula: 
C
17
H
13
ClN
4

Molecular Weight: 
308.76 

CAS Number: 
28981-97-7 

PHARMACOLOGY  
Alprazolam  is  an  anti-anxiety, benzodiazepine derivative
chemically and pharmacologically related to 
other drugs of this class. 

Pharmacological properties of alprazolam in
animals appear similar to those of other benzodiazepines, 
that is, it produces significant anxiolytic, muscle
relaxant, sleep promoting and anticonvulsant effects in 
appropriate animal models. 

The exact site and mechanism of action of benzodiazepines is unknown.  It is known that they act within 
the central nervous system as selective depressants. 

Clinical studies in healthy volunteers at doses of up to 4 mg/day  alprazolam,  and in patients with panic 
disorder at doses of up to 10
mg/day  alprazolam, only produce effects which can be considered
to be 
extensions of its pharmacological activities.  No
clinically significant effects on the cardiovascular or 
respiratory systems were observed.  Alprazolam at doses of up
to 10 mg/day does not clinically affect 
laboratory parameters or vital signs. 

Sleep laboratory studies in man showed that alprazolam decreased sleep latency, increased duration of 
sleep and decreased the number of nocturnal awakenings.
 Alprazolam produced small decreases in both 
stages 3-4 and REM sleep. 

PHARMACOKINETICS  
_Absorption _ 
Following oral administration to fasting su