Country: Australia
Language: English
Source: Department of Health (Therapeutic Goods Administration)
Propolis dry extract
Chalmers Dale & Co Pty Ltd
Propolis dry extract
Medicine Listed
VEPESID ® 1 VEPESID ® _etoposide (e-TOE-poe-side) _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about VEPESID. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking VEPESID against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. WHAT VEPESID IS USED FOR VEPESID is used to treat lung cancer, leukaemia (blood cancer) and cancer of the lymph glands. VEPESID contains ETOPOSIDE, an anti-cancer medicine. It interferes with the development of cells and causes cell death, particularly in cancer cells. VEPESID may be used alone or in combination with other medicines to treat cancer. Your doctor will inform you if this is necessary. Your doctor may have prescribed VEPESID for another reason. Ask your doctor if you have any questions about why VEPESID was prescribed for you. BEFORE YOU ARE GIVEN VEPESID _WHEN YOU MUST NOT BE GIVEN _ _IT _ DO NOT TAKE VEPESID IF YOU HAVE AN ALLERGY TO VEPESID, OR ANY OF THE INGREDIENTS LISTED AT THE END OF THIS LEAFLET, UNLESS YOU HAVE DISCUSSED IT WITH YOUR DOCTOR. Symptoms of an allergic reaction may include: • chills/fever • fast heart beat • difficulty in breathing, shortness of breath • dizziness or lightheadedness DO NOT TAKE VEPESID IF YOU HAVE, OR HAVE HAD ANY OF THE FOLLOWING MEDICAL CONDITIONS, UNLESS YOU HAVE DISCUSSED IT WITH YOUR DOCTOR: • liver problems • kidney problems • your immune system is not working properly (you get a lot of infections requiring treatment with antibiotics) • a blood disorder with a reduced number of white blood cells • a blood disorder in which there is a decreased number of red blood cells • a blood disorder with a low blood platelet count • lowered immunity due to treatment with medicines such as Read the complete document
VEPESID PI V7.0 1 AUSTRALIAN PRODUCT INFORMATION - VEPESID (ETOPOSIDE) 1 NAME OF MEDICINE Etoposide. 2 QUALITATIVE AND QUANTITATIVE COMPOSITION VEPESID capsules contain 50 or 100 mg etoposide. Excipients with known effect: Each 50 mg capsule contains 930 mcg of sodium ethyl hydroxybenzoate and 470 mcg sodium propyl hydroxybenzoate. Each 100 mg capsule contains 1.22 mg of sodium ethyl hydroxybenzoate and 610 mcg sodium propyl hydroxybenzoate. For the full list of excipients, see section 6.1 List of excipients. 3 PHARMACEUTICAL FORM Opaque, pink, soft gelatin capsule. 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS_ _ VEPESID (etoposide) is indicated for use in the treatment of: 1. Small cell carcinoma of the lung. 2. Acute monocytic and myelomonocytic leukaemia. 3. Hodgkin's disease. 4. Non-Hodgkin's lymphoma. 4.2 DOSE AND METHOD OF ADMINISTRATION_ _ Biological activity appears to be schedule dependent with multiple dosage over 3-5 days showing superiority over single dose administration. ADULT Absorption from the oral route is variable (range 17-74% of intravenous dose in one trial, 25-80% in another, the corresponding means being 50 and 53%). Dosages should be titrated to achieve maximum therapeutic effect and to minimise toxicity. The suggested starting dose is approximately 100-200 mg/m 2 /day on days 1 to 5. Dosage should be modified to take into account the myelosuppressive effects of other drugs in the combination or the effects of prior X-ray therapy or chemotherapy, which may have compromised bone marrow reserve. VEPESID PI V7.0 2 Total dose should not exceed 650 mg/m 2 per course. Capsules should be taken on an empty stomach. PAEDIATRIC Specific paediatric dosages have not been evaluated. USE IN THE ELDERLY As for adults. However see Section 4.2 DOSE AND METHOD OF ADMINISTRATION Impaired Liver Function and Impaired Renal Function. IMPAIRED LIVER FUNCTION There are indications that patients with severely impaired liver function (as expressed by an elevation of serum bilirubin above 85 micromoles/L and Read the complete document