Cefazolin Multichem

Country: New Zealand

Language: English

Source: Medsafe (Medicines Safety Authority)

Active ingredient:

Cefazolin sodium 524mg equivalent to cephazolin 500 mg;  

Available from:

Multichem NZ Limited

INN (International Name):

Cefazolin sodium 524 mg (= cephazolin 500 mg)

Dosage:

500 mg

Pharmaceutical form:

Powder for injection

Composition:

Active: Cefazolin sodium 524mg equivalent to cephazolin 500 mg  

Units in package:

Vial, single dose, 10 x 500mg vials, 5 g

Class:

Prescription

Prescription type:

Prescription

Manufactured by:

Qilu Antibiotics Pharmaceutical Co Ltd

Product summary:

Package - Contents - Shelf Life: Vial, single dose, 10 x 500mg vials - 5 g - 36 months from date of manufacture stored at or below 25°C protect from light and moisture

Authorization date:

2005-11-18

Patient Information leaflet

M-CEFAZOLIN - CMI 
Cefazolin sodium 500mg and 1g Powder for Injection 
_CONSUMER MEDICINE INFORMATION _
_WHAT IS IN THIS LEAFLET _
This leaflet is designed to provide you with answers to some common
questions about 
this medicine. It does not contain all the available information and
does not take the 
place of talking with your doctor.  
All medicines have risks and benefits.  
Your doctor has more information about this medicine
than is contained in this leaflet. 
Also, your doctor has had the benefit of taking a full and detailed
history from you and 
is in the best position to make an expert judgment to meet your
individual needs.  
IF YOU HAVE ANY CONCERNS ABOUT BEING GIVEN THIS MEDICINE, TALK
TO YOUR DOCTOR OR 
HEALTH CARE PROFESSIONAL.  
KEEP THIS LEAFLET WITH THIS MEDICINE. You may need to read it
again.  
_WHAT M-CEFAZOLIN IS GIVEN FOR _
m-Cefazolin is an antibiotic used to treat serious
infections in different parts of the body 
caused by bacteria.  
m-Cefazolin is also used prior to certain surgeries to prevent
infection. 
m-Cefazolin works by killing the bacteria that are causing your
infection.  
m-Cefazolin belongs to a group of antibiotics called
cephalosporin’s (pronounced kef-
al-o-spor-in).  
Your doctor may have prescribed m-Cefazolin for another
reason. ASK YOUR DOCTOR IF 
YOU HAVE ANY QUESTIONS ABOUT WHY M-CEFAZOLIN HAS BEEN PRESCRIBED
FOR YOU.  
m-Cefazolin is not recommended for use in premature infants and in
infants under one 
month.  
This medicine is available only with a doctor's prescription.  
_BEFORE YOU ARE GIVEN M-CEFAZOLIN _
TELL YOUR DOCTOR OR HEALTH CARE PROFESSIONAL IF YOU HAVE ANY OF
THE FOLLOWING 
CONDITIONS OR IF YOU HAVE EVER EXPERIENCED ANY OF THESE
CONDITIONS.  
WHEN YOU MUST NOT BE GIVEN M-CEFAZOLIN 
DO NOT USE M-CEFAZOLIN IF YOU HAVE HAD AN ALLERGIC REACTION TO
CEFAZOLIN SODIUM.  
Signs of an allergic reaction may include a skin rash,
itching, shortness of breath or 
swelling of the face, l

Summary of Product characteristics

NEW ZEALAND DATA SHEET 
_M_-CEFAZOLIN 
Cefazolin, Powder for injection, 500mg, 1g and 2g 
Cefazolin, Injection with diluent, 500mg and 1g 
Please refer to the Medsafe website (www.medsafe.govt.nz) for the
most recent 
version of this prescribing information. 
Page 1 of 12 

PRESENTATION 
m-Cefazolin is a white to off-white powder which reconstitutes with
Sterile Water for 
Injection to give a colourless solution. 

m-Cefazolin 500 mg vial contains cefazolin sodium equivalent to 500
mg of cefazolin. 

m-Cefazolin 1 g vial contains cefazolin sodium equivalent to 1 g of
cefazolin. 

m-Cefazolin 2 g vial contains cefazolin sodium equivalent to 2 g of
cefazolin. 

USES 
ACTIONS 
Cefazolin sodium is a semisynthetic cephalosporin for intramuscular or
intravenous 
administration.  _In vitro _tests demonstrate that the bactericidal
action of 
cephalosporins results from inhibition of cell-wall synthesis. 

Cefazolin is active against the following organisms _in vitro _and
in clinical infections: 
_Staphylococcus aureus _
(including penicillinase-producing strains); _Staphylococcus _
_epidermidis_
; Group A β -haemolytic streptococci and other strains of
streptococci 
(many strains of enterococci are resistant); _Streptococcus
pneumoniae;_ _Escherichia _
_coli;_
  _Klebsiella  _sp.;  _Proteus mirabilis; _  _Haemophilus
influenzae_;  _Enterobacter _
_aerogenes._

Most strains of indole-positive _Proteus (Proteus vulgaris),
Enterobacter cloacae, _
_Morganella morganii, _
and  _Providencia rettgeri _are resistant. Methicillin-resistant 
staphylococci,  _Serratia, Pseudomonas _and  _Acinetobacter_  _calcoaceticus  _(formerly 
_Mima _
and _Herellea _sp.) are almost uniformly resistant to cefazolin. 

DISC SUSCEPTIBILITY TESTS 
Quantitative methods that require measurements of
zone diameters give the most 
precise estimates of antibiotic susceptibility. One such procedure
has been 
recommended for use with discs for testing