CEFAXONE FOR INJECTION 1 gvial

Country: Singapore

Language: English

Source: HSA (Health Sciences Authority)

Active ingredient:

CEFTRIAXONE SODIUM EQV CEFTRIAXONE

Available from:

ZYFAS PHARMA PTE LTD

ATC code:

J01DD04

Dosage:

1 g/vial

Pharmaceutical form:

INJECTION, POWDER, FOR SOLUTION

Composition:

CEFTRIAXONE SODIUM EQV CEFTRIAXONE 1 g/vial

Administration route:

INTRAMUSCULAR

Prescription type:

Prescription Only

Manufactured by:

SHIN POONG PHARMACEUTICAL CO LTD

Authorization status:

ACTIVE

Authorization date:

1999-09-11

Summary of Product characteristics

Third Generation Cephalosporins
CEFAXONE INJECTION
500MG, 1G
CEFTRIAXONE SODIUM
■
COMPOSITION
: Each vial contains
Ceftriaxone sodium……..……....... 500mg (potency)
………………… 1g (potency)
■ DESCRIPTION
CEFAXONE INJECTION is a white to pale yellow powder
in a colorless transparent vial. Each box comes
with 10 vials and a package insert.
■ PHARMACOLOGY
The bactericidal activity of ceftriaxone results from inhibition of
bacterial cell wall synthesis.
Ceftriaxone exerts in vitro activity against a wide range of
gram-negative and gram-positive
micro-organisms. Ceftriaxone is highly stable to most ß-lactamases,
both penicillinases and
cephalosporinases, of gram-positive and gram-negative bacteria.
Ceftriaxone is usually active
against the following micro-organisms in vitro and in clinical
infections.
Gram-positive aerobes
Staphylococcus aureus
(methicillin-sensitive), Staphylococci coagulase-negative,
Streptococcus
pyogenes
(ß-hemolytic, group A),
Streptococcus agalactiae
(ß-hemolytic, group B), ß-hemolytic
Streptococci (non-group A or B),
Streptococcus viridans, Streptococcus pneumoniae.
Note
: Methicillin-resistant
Staphylococcus
spp. is resistant to cephalosporins, including ceftriaxone.
In general,
Enterococcus faecalis, Enterococcus faecium
and
Listeria monocytogenes
are resistant.
Gram-negative aerobes
Acinetobacter lwoffi, Acinetobacter anitratus
(mostly A. baumanii)
*, Aeromonas hydrophila,
Alcaligenes faecalis, Alcaligenes odorans, Alcaligenes
-like bacteria
, Borrelia burgdorferi,
Capnocytophaga
spp.
, Citrobacter diversus (
including C.
amalonaticus), Citrobacter freundii*,
Escherichia coli, Enterobacter aerogenes*, Enterobacter cloacae*,
Enterobacter
spp. (other)*
,
Haemophilus ducreyi, Haemophilus influenzae, Haemophilus
parainfluenzae, Hafnia alvei, Klebsiella
oxytoca, Klebsiella pneumoniae**, Moraxella catarrhalis
(former
Branhamella catarrhalis), Moraxella
osloensis, Moraxella
spp. (other),
Morganella morganii, Neisseria gonorrhoea, Neisseria
meningitidis, Pasteurella multoci