AVet Isoflurane

Country: Australia

Language: English

Source: APVMA (Australian Pesticides and Veterinary Medicines Authority)

Active ingredient:

ISOFLURANE

Available from:

AVET HEALTH LIMITED

Pharmaceutical form:

PARENTERAL LIQUID/SOLUTION/SUSPENSION

Composition:

ISOFLURANE ANAESTHETIC Active 1.0 ml/ml

Units in package:

6 x 100mL; 6 x 250mL

Class:

VM - Veterinary Medicine

Therapeutic area:

ANAESTHETICS/ANALGESICS

Product summary:

Poison schedule: 4; Withholding period: ; Host/pest details: BIRDS - ORNAMENTAL: [INHALATION ANAESTHETIC]; CAT: [INHALATION ANAESTHETIC]; DOG: [INHALATION ANAESTHETIC]; HORSE: [INHALATION ANAESTHETIC]; REPTILE: [INHALATION ANAESTHETIC]; SMALL MAMMALS: [INHALATION ANAESTHETIC]

Authorization status:

Registered

Authorization date:

2023-07-01

Patient Information leaflet

Product Name: eLabel
APVMA Approval No:
AVet Isoflurane
92735/136471
Label Name:
AVet Isoflurane
Signal Headings:
PRESCRIPTION ANIMAL REMEDY
KEEP OUT OF REACH OF CHILDREN
FOR ANIMAL TREATMENT ONLY
READ SAFETY DIRECTIONS BEFORE OPENING OR USING
Constituent
Statements:
1 mL/mL Isoflurane
Claims:
Inhalation anaesthetic for use in horses, cats, dogs, ornamental
birds, reptiles and small
mammals
Net Contents:
250 mL
Directions for Use:
Restraints:
NOT TO BE USED in horses intended for human consumption.
Contraindications:
DO NOT use in animals with a known sensitivity to isoflurane or with a
known susceptibility
to malignant hyperthermia.
Precautions:
When using isoflurane to anaesthetise an animal with a head injury,
consideration should
be given as to whether artificial ventilation is appropriate to
maintain normal CO2 levels so
that cerebral blood flow does not increase.
In man, the action of muscle relaxants, especially those of the
non-depolarising type such
as atracurium, pancuronium or vecuronium is enhanced by isoflurane.
Similar potentiation
might be expected to occur in the target species, although there is
little direct evidence to
this effect.
The concurrent use of sedative or analgesic drugs is likely to reduce
the level of isoflurane
required to induce and maintain anaesthesia. For example, opiates,
alpha-2 agonists,
acepromazine, and benzodiazepines have been reported to reduce the MAC
values. RLP APPROVED
For Official Use Only
Particular caution should be exercised if administering a midazolam
ketamine combination
to an animal already anaesthetised with isoflurane.
Isoflurane has been reported to interact with dry carbon dioxide
absorbents to form carbon
monoxide. In order to minimise the risk of formation of carbon
monoxide in rebreathing
circuits and the possibility of elevated carboxyhaemoglobin levels,
carbon dioxide
absorbents should not be allowed to dry out.
AVet Isoflurane has been safely used for anaesthesia during Caesarean
section in the
dog and the cat. Reproduction studies have been perfor