AVELOX

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Moxifloxacin

Available from:

Bayer Australia Ltd

Class:

Medicine Registered

Patient Information leaflet

AVELOX
®
 TABLETS CMI                                  

 1 
AVELOX
®
 TABLETS 
(AV·E·LOX) 
_moxifloxacin hydrochloride  _

CONSUMER MEDICINE INFORMATION 

WHAT IS IN THIS 
LEAFLET 
This leaflet answers some common 
questions about Avelox tablets.  

It does not contain all of the 
available information. It does not 
take the place of talking to your 
doctor or pharmacist. 

All medicines have risks and 
benefits. Your doctor has weighed 
the risks of you taking Avelox 
against the benefits they expect it 
will have for you. 

IF YOU HAVE ANY CONCERNS ABOUT 
TAKING THIS MEDICINE, ASK YOUR 
DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET WITH THE 
MEDICINE.   
You may need to read it again. 
WHAT AVELOX IS USED 
FOR 
Avelox tablets are used in adults for 
the treatment of infections of the 
lungs, airways and sinuses.  

In certain infections, you may 
require treatment with Avelox IV 
injection followed by a course of 
Avelox tablets e.g. severe and 
complicated skin and skin structure 
infections.  

Even if you have read the 
Consumer Medicine Information 
for Avelox IV, you should read this 
leaflet as well as it contains 
information specific to the tablets. 

Avelox tablets contain the active 
ingredient, moxifloxacin, which is 
an antibiotic belonging to a group 
of medicines called quinolones. 
These antibiotics work by killing 
the bacteria that are causing your 
infection. 

Avelox tablets will not work 
against infections caused by viruses 
such as colds or the flu. 

Avelox tablets are available by 
prescription only. 

ASK YOUR DOCTOR IF YOU HAVE ANY 
QUESTIONS ABOUT WHY THIS 
MEDICINE HAS BEEN PRESCRIBED FOR 
YOU. 
Your doctor may have prescribed it 
for another reason. 
BEFORE YOU TAKE 
AVELOX 
_WHEN YOU MUST NOT TAKE IT _
DO NOT TA

Summary of Product characteristics

111013 Avelox PI                            

Page 1 of 22

PRODUCT INFORMATION 
AVELOX
®

(MOXIFLOXACIN HYDROCHLORIDE, BAYER) 

NAME OF THE MEDICINE 
Moxifloxacin hydrochloride (CAS number: 186826-86-8).
 Its empirical formula is C
21
H
23
FN
3
O
4 * 
HCl and has a molecular weight of 437.9. Moxifloxacin,
a fluoroquinolone, differs from other 
quinolones in that it has a methoxy function at the
8-position and an _S,S_  configurated 
diazabicyclononyl ring moiety at the 7-position. Its chemical name is 1-cyclopropyl-7-{(_S,S_)-2,8-
diaza-bicyclo[4.3.0]non-8-yl}-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 
hydrochloride. It is a pale yellow substance. The substance
shows no melting point but it 
decomposes above 250°C. It is sparingly soluble in water and methanol, slightly soluble in HCl 
and ethanol, and practicably insoluble in acetone and toluene.  It
has the following chemical 
structure: 

DESCRIPTION 
Avelox  (moxifloxacin hydrochloride) is a synthetic broad
spectrum antibacterial agent and is 
available as Avelox  tablets for oral administration, and
as Avelox  IV infusion solution for 
intravenous administration.  
Avelox  tablets are available as a 400 mg film-coated tablet.  Besides the active ingredient, 
Avelox  tablets also contain the following excipients: microcrystalline cellulose, croscarmellose 
sodium, lactose, magnesium stearate, ferric oxide, hypromellose,
macrogol 4000, and titanium 
dioxide. 
Avelox IV is available in ready-to-use 250 mL (containing 400 mg
of moxifloxacin) flexibags or 
glass infusion bottles, as a sterile, preservative free
aqueous solution of moxifloxacin 
hyd