Country: Malaysia
Language: English
Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
MINOXIDIL
Asumed Biotech Sdn. Bhd.
MINOXIDIL
60 ml
Chen Ho Pharmaceutical Co., Ltd. Sinying Plant
_Consumer Medication Information Leaflet_ _(RiMUP) _ ASU MINOXIDIL TOPICAL SOLUTION 5% W/V Minoxidil 50mg/ml Page 1 of 2 WHAT IS IN THIS LEAFLET:_ _ a) What Asu Minoxidil is used for b) How Asu Minoxidil works c) Before you use Asu Minoxidil d) How to use Asu Minoxidil e) While you are using Asu Minoxidil f) Side effects g) Storage and disposal of Asu Minoxidil h) Product description i) Manufacturer & Product Registration Holder j) Date of revision WHAT ASU MINOXIDIL IS USED FOR Asu Minoxidil is used to stimulate hair growth and is used in the treatment of hair loss (alopecia androgenetica) HOW ASU MINOXIDIL WORKS The mechanism by which minoxidil stimulates hair growth is not fully understood, but minoxidil can reverse the hair loss process of androgenetic alopecia by increasing the diameter of the hair shaft, stimulating anagen growth, prolonging the anagen phase and stimulating anagen recovery from the telegon phase. As a peripheral vasodilator, minoxidil enhances microcirculation to hair follicles. The Vascular Endothelial Growth Factor (VEGF) is stimulated by minoxidil and VEGF is presumably responsible for the increased capillary fenestration, indicative of a high metabolic activity that observed during the anagen phase. BEFORE YOU USE ASU MINOXIDIL _-WHEN YOU MUST NOT USE IT _ Do not use Asu Minoxidil if you are known allergic (hypersensitive) to any ingredients in this medicine. Should not be applied to inflamed scalp skin or areas affected by psoriasis, severe sunburn, or severe excoriations, because of the risk of increased absorption. _Pregnancy and lactation _ Do not take Asu Minoxidil if you are pregnant, trying to get pregnant or think you may be pregnant. Do not take Asu Minoxidil if you are breastfeeding. Ask your doctor or pharmacist for advice before taking any medicine. _-BEFORE YOU START TO USE IT _ Tell your doctor or pharmacist if: You are pregnant or plan to get pregnant. You are breast feeding. -_TAKING OTHER MEDICINES_ Tell your doctor if you are taking any othe Read the complete document
Font Size 7, Times New Roman ASU MINOXIDIL TOPICAL SOLUTION 5% W/V COMPOSITION Each ml contains: Minoxidil 50 mg PRODUCT DESCRIPTION A colorless to pale yellow transparent liquid with alcoholic smell. INDICATION Asu Minoxidil Topical Solution 5% w/v is exclusively indicated for the treatment of alopecia androgenetica in males and females. Asu Minoxidil Topical Solution 5% w/v stimulates hair growth and stabilizes hair loss in patients with alopecia androgenetica. PHARMACOLOGICAL PROPERTIES ATC CODE: D11AX01 Pharmacotherapeutic group: Dermatological preparations containing minoxidil PHARMACODYNAMIC PROPERTIES The mechanism by which minoxidil stimulates hair growth is not fully understood, but minoxidil can reverse the hair loss process of androgenetic alopecia by increasing the diameter of the hair shaft, stimulating anagen growth, prolonging the anagen phase and stimulating anagen recovery from the telegon phase. As a peripheral vasodilator, minoxidil enhances microcirculation to hair follicles. The Vascular Endothelial Growth Factor (VEGF) is stimulated by minoxidil and VEGF is presumably responsible for the increased capillary fenestration, indicative of a high metabolic activity, observed during the anagen phase. PHARMACOKINETIC PROPERTIES About 0.3 to 4.5% of a topical dose of minoxidil is absorbed from intact scalp. Minoxidil is not bound to plasma proteins. It is distributed into breast milk. Minoxidil is extensively metabolised by the liver. It requires sulfation to become active, but the major metabolite is a glucuronide conjugate. Minoxidil is excreted predominantly in the urine mainly in the form of metabolites. Minoxidil and its metabolites are dialysable, although the pharmacological effect is not reversed. RECOMMENDED DOSAGE ROUTE OF ADMINISTRATION : For external use only. Use Asu Minoxidil Topical Solution 5%w/v only as directed. Do not apply Asu Minoxidil Topical Solution 5%w/v to any other area of the body. A total dose of 1 mL Asu Minoxidil Topical Solution 5%w/v should be applied twice per day t Read the complete document