ASPIRIN WITH STOMACH GUARD TABLET

Country: Canada

Language: English

Source: Health Canada

Active ingredient:

ACETYLSALICYLIC ACID; CALCIUM CARBONATE; MAGNESIUM OXIDE; MAGNESIUM CARBONATE

Available from:

BAYER INC CONSUMER CARE

ATC code:

N02BA51

INN (International Name):

ACETYLSALICYLIC ACID, COMB EXCL PSYCHOLEPTICS

Dosage:

325MG; 160MG; 63MG; 34MG

Pharmaceutical form:

TABLET

Composition:

ACETYLSALICYLIC ACID 325MG; CALCIUM CARBONATE 160MG; MAGNESIUM OXIDE 63MG; MAGNESIUM CARBONATE 34MG

Administration route:

ORAL

Units in package:

36

Prescription type:

OTC

Therapeutic area:

SALICYLATES

Product summary:

Active ingredient group (AIG) number: 0424185003; AHFS:

Authorization status:

CANCELLED POST MARKET

Authorization date:

2012-07-12

Summary of Product characteristics

PRODUCT MONOGRAPH
ASPIRIN*
(acetylsalicylic acid tablets, USP)
(325mg, 500mg)
ASPIRIN*
(acetylsalicylic acid delayed release tablets, USP)
(81mg, 325mg, 500mg, 650mg)
Analgesic, anti-inflammatory, antipyretic and
platelet aggregation inhibitor
BAYER INC.
DATE OF REVISION:
Toronto, Ontario
July 26, 2004
©Copyright Bayer Inc. 2000
Control# 092023
NAME OF DRUG
ASPIRIN*
(acetylsalicylic acid tablets, USP)
THERAPEUTIC OR PHARMACOLOGICAL CLASSIFICATION
Analgesic, anti-inflammatory, anti-pyretic and platelet aggregation
inhibitor.
ACTIONS
Acetylsalicylic acid (ASA) interferes with the production of
prostaglandins in various organs
and tissues through acetylation of the enzyme cyclo-oxygenase.
Prostaglandins are
themselves powerful irritants and produce headaches and pain on
injection in man.
Prostaglandins also appear to sensitize pain receptors to other
noxious substances such as
histamine and bradykinin. By preventing the synthesis and release of
prostaglandins in
inflammation, ASPIRIN* may avert the sensitization of pain receptors.
The antipyretic activity of ASA is due to its ability to interfere
with the production of
prostaglandin E
1
in the brain. Prostaglandin E
1
is one of the most powerful pyretic agents
known.
The inhibition of platelet aggregation by ASA is due to its ability to
interfere with the
production of thromboxane A
2
within the platelet. Thromboxane A
2
is, largely, responsible
for the aggregating properties of platelets.
- 3 -
INDICATIONS
ASPIRIN* (acetylsalicylic acid, ASA) is indicated for the relief of
pain, fever and
inflammation of a variety of conditions such as influenza, common
cold, low back and neck
pain, dysmenorrhea, headache, toothache, sprains and strains,
fractures, myositis,
neuralgia, synovitis, arthritis, bursitis, burns, injuries, following
surgical and dental
procedures. ASPIRIN® Extra Strength is also indicated for relief of
migraines including pain
and the associated symptoms of photophobia (sensitivity to light) and
phonophobia
(sensitivity to sound), and improves overall