ANTISEDAN SOLUTION

Country: Canada

Language: English

Source: Health Canada

Active ingredient:

ATIPAMEZOLE HYDROCHLORIDE

Available from:

ORION CORPORATION

Dosage:

5MG

Pharmaceutical form:

SOLUTION

Composition:

ATIPAMEZOLE HYDROCHLORIDE 5MG

Administration route:

INTRAMUSCULAR

Units in package:

10ML

Prescription type:

Prescription

Therapeutic group:

DOGS

Product summary:

Active ingredient group (AIG) number: 0131492001

Authorization status:

APPROVED

Authorization date:

1998-04-15

Patient Information leaflet

SUPPLIER
SMALLEST FONT USED
PAR NUMBER
REASON FOR REVISION:
Company name change to Zoetis, to be phased in without
jeopardising supply, reorder Pfizer components in minimum
quantities if required.
BLACK
28 APR 2014
13:00
PROOF N
O
COMPONENT
COLOUR BAR POSITIONS
DRAWING N
O
PHARMA CODE
01
Leaflet
N/A
N/A
As Supplied
Orion
Body: 10 pt. Codes: 8 pt
PAR-2014-0020299
MARKET
SUPPLIER N
O
PERIGORD N
O
BARCODE N
O
PAGES
DIMENSIONS
NOTES
COLOURS
Canada
105848-7
227974
N/A
148 x 600 mm - Image Prints @ 100%
N/A
01
DESCRIPTION
ANTISEDAN SSOL 5 MG/ML 10 ML GBTL 1 EA ENG
1 of 2
DOSAGE AND ADMINISTRATION: Antisedan
is administered intramuscularly regardless of
the route used for Dexdomitor or Domitor. The
concentration of Antisedan has been formulated
such that the volume of injection is the same
(mL for mL) as the recommended dose volume
of Dexdomitor or Domitor, and may be given
at any time following Dexdomitor or Domitor
administration. Although injection volumes
are the same, the concentration of Antisedan
(5.0 mg/mL) is 10 times that of Dexdomitor
(0.5 mg/mL) and 5 times that of Domitor
(1.0 mg/mL). Dogs that are sedated but ambulatory
may be treated with Antisedan, if warranted.
The dosage of Antisedan is calculated based upon
body surface area. Use the following tables to
determine the proper injection volume based
on bodyweight. Note that the mcg/kg dosage
decreases as body weight increases.
Table 1: Atipamezole dosing for reversal of
IV dexmedetomidine- or medetomidine-induced
sedation/analgesia:
Dose table for Antisedan when
dexmedetomidine or medetomidine
is given IV
Bodyweight
(kg)
Dose =
mcg/kg
Volume = mL
Antisedan
2-2.9
300
0.1
3-3.9
250
0.15
4-4.9
230
0.2
5-9.9
200
0.3
10-14.9
170
0.4
15-19.9
150
0.5
20-24.9
140
0.6
25-29.9
130
0.7
30-36.9
120
0.8
37-44.9
110
0.9
45-49.9
105
1.0
50-59.9
100
1.1
60-64.9
95
1.2
65-74.9
93
1.3
75-79.9
91
1.4
>80
90
1.5
Table 2: Atipamezole dosing for reversal of IM
dexmedetomidine- or medetomidine-induced
sedation/analgesia:
Dose table for Antisedan when
dexmedetomidine or medetom