Amikin 500 Injection

Country: Bangladesh

Language: English

Source: DGDA (Directorate General of Drug Administration)

Active ingredient:

Amikacin

Available from:

Incepta Pharmaceuticals Ltd.

INN (International Name):

Amikacin

Dosage:

500 mg/2 ml

Pharmaceutical form:

Injection

Patient Information leaflet

AMIKIN (AMIKACIN)
THERAPEUTIC GROUP: ANTI BACTERIAL
PRESENTATION
Amikin 100 IM/IV Injection: Each 2ml ampoule contains 100 mg Amikacin
as Amikacin Sulfate
USP.
Amikin 500 IM/IV Injection: Each 2ml ampoule contains 500 mg Amikacin
as Amikacin Sulfate
USP.
DESCRIPTION
Amikacin Sulfate is a semi-synthetic aminoglycoside antibiotic.
Amikacin is active in vitro against
Pseudomonas species, Escherichia coli, Proteus species, Providencia
species, Klebsiella-
Enterobacter species, Acinetobacter species, and Citrobacter freundii.
When strains of the above
organisms are found to be resistant to other aminoglycosides,
including Gentamicin, TobrAmykin
and KanAmykin, many are susceptible to Amikacin. Amikacin sulfate is
active in vitro against
penicillinase and nonpenicillinase-producing Staphylococcus species
including methicillin-resistant
strains.
INDICATIONS
Amikacin is indicated in the short-term treatment of serious
infections due to susceptible strains of
Gram-negative bacteria. It is effective in bacterial septicemia
(including neonatal sepsis); in serious
infections of the respiratory tract, bones and joints, central nervous
system (including meningitis)
and skin and soft tissue; intra abdominal infections (including
peritonitis); and in bums and post
operative infections (including post-vascular surgery). Amikacin is
also effective in serious
complicated and recurrent urinary tract infections due to susceptible
Gram-negative organisms. It
may be considered as initial therapy in suspected Gram-negative
infections and therapy may be
instituted before obtaining the results of susceptibility. Amikacin is
also effective in infections
caused by Gentamycln and/or TobrAmykin resistant strains of
Gram-negative organisms. Amikacin
has also been shown to be effective in Staphylococcal infection and
may be considered as initial
therapy under certain condition in the treatment of known suspected
Staphylococcal disease such as,
severe infections where the causative organism may either a
Gram-negative bacterium or
Staphylococcus i