Allergenic Extract

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

CHAETOMIUM GLOBOSUM (UNII: 5016WB8B8A) (CHAETOMIUM GLOBOSUM - UNII:5016WB8B8A)

Available from:

Antigen Laboratories, Inc.

INN (International Name):

CHAETOMIUM GLOBOSUM

Composition:

CHAETOMIUM GLOBOSUM 0.05 g in 1 mL

Administration route:

SUBCUTANEOUS

Prescription type:

PRESCRIPTION DRUG

Therapeutic indications:

Allergenic extract is used for diagnostic testing and for the treatment (immunotherapy) of patients whose histories indicate that upon natural exposure to the allergen, they experience allergic symptoms. Confirmation is determined by skin testing. Diagnostic use of allergenic extracts usually begins with direct skin testing. This product is not intended for treatment of patients who do not manifest immediate hypersensitivity reactions to the allergenic extract following skin testing. Do not administer in the presence of diseases characterized by bleeding diathesis. Individuals with autoimmune disease may be at risk of exacerbating symptoms of the underlying disease, possibly due to routine immunization. Patients who have experienced a recent myocardial infarction may not be tolerant of immunotherapy. Children with nephrotic syndrome probably should not receive injections due to immunization causing exacerbation of nephrotic disease.

Product summary:

Stock concentrates are available in concentrations of 2-10% or weight/volume (w/v) of 1:50, 1:33, 1:20 or 1:10. Some juicy or liquid foods are available at 1:1 volume/volume (v/v) extraction ratio. Fresh egg white extract is available at 1:9 v/v extraction ratio. Antigen E content of ragweed mixtures ranges from 46-166 U/ml for Ragweed Mixture (Short/Giant/Western/Southern Ragweed), 47-239 U/ml for Short/Giant/Western Ragweed Mixture, and 106-256 U/ml for Short/Giant Ragweed Mixture. Refer to container label for actual Antigen E content. Extract (stock concentrate) is supplied in 10, 30 and 50 ml containers. Extracts in 5 ml dropper bottles are available for prick-puncture testing. To insure maximum potency for the entire dating period, all stock concentrates contain 50% glycerine v/v.

Authorization status:

Biologic Licensing Application

Summary of Product characteristics

CHAETOMIUM - CHAETOMIUM INJECTION, SOLUTION
CEPHALOSPORIUM - CEPHALOSPORIUM INJECTION, SOLUTION
CLADOSPORIUM HERBARUM - CLADOSPORIUM HERBARUM INJECTION, SOLUTION
CURVULARIA - CURVULARIA INJECTION, SOLUTION
BOTRYTIS - BOTRYTIS INJECTION, SOLUTION
ASPERGILLUS NIGER - ASPERGILLUS NIGER INJECTION, SOLUTION
BERMUDA GRASS SMUT - BERMUDA GRASS SMUT INJECTION, SOLUTION
HELMINTHOSPORIUM - HELMINTHOSPORIUM INJECTION, SOLUTION
JOHNSON GRASS SMUT - JOHNSON GRASS SMUT INJECTION, SOLUTION
FUSARIUM OXYSPORUM - FUSARIUM OXYSPORUM INJECTION, SOLUTION
EPICOCCUM - EPICOCCUM INJECTION, SOLUTION
HORMODENDRUM - HORMODENDRUM INJECTION, SOLUTION
NUMBER FOUR MOLD MIXTURE - NUMBER FOUR MOLD MIXTURE INJECTION,
SOLUTION
GRASS SMUT MIXTURE - GRASS SMUT MIXTURE INJECTION, SOLUTION
GRAIN SMUT MIXTURE - GRAIN SMUT MIXTURE INJECTION, SOLUTION
A MOLD MIXTURE - A MOLD MIXTURE INJECTION, SOLUTION
MICROSPORUM CANIS - MICROSPORUM CANIS INJECTION, SOLUTION
B MOLD MIXTURE - B MOLD MIXTURE INJECTION, SOLUTION
ASPERGILLUS MIXTURE - ASPERGILLUS MIXTURE INJECTION, SOLUTION
ALTERNARIA ALTERNATA - ALTERNARIA ALTERNATA INJECTION, SOLUTION
NUMBER TEN MOLD MIXTURE - NUMBER TEN MOLD MIXTURE INJECTION, SOLUTION
ASPERGILLUS FUMIGATUS - ASPERGILLUS FUMIGATUS INJECTION, SOLUTION
MUCOR MIXTURE - MUCOR MIXTURE INJECTION, SOLUTION
MONILIA MIXTURE - MONILIA MIXTURE INJECTION, SOLUTION
TRICHOPHYTON MIXTURE - TRICHOPHYTON MIXTURE INJECTION, SOLUTION
PENICILLIUM MIXTURE - PENICILLIUM MIXTURE INJECTION, SOLUTION
PENICILLIUM NOTATUM - PENICILLIUM NOTATUM INJECTION, SOLUTION
PHOMA - PHOMA INJECTION, SOLUTION
NIGROSPORA - NIGROSPORA INJECTION, SOLUTION
PULLULARIA - PULLULARIA INJECTION, SOLUTION
CANDIDA ALBICANS - CANDIDA ALBICANS INJECTION, SOLUTION
MYCOGONE PERNICIOSA - MYCOGONE PERNICIOSA INJECTION, SOLUTION
MUCOR RACEMOSUS - MUCOR RACEMOSUS INJECTION, SOLUTION
TRICHODERMA - TRICHODERMA INJECTION, SOLUTION
STACHYBOTRYS - STACHYBOTRYS INJECTION, SOLUTION
TRICHOPHYTON RUBRUM - TRICHOPHYTON RUBRUM INJECTION, SOLUTION
RHIZOPUS - RHIZOPUS INJECTION, SOLUTION
PAECILOMYCES - PAECI