Country: United Kingdom
Language: English
Source: MHRA (Medicines & Healthcare Products Regulatory Agency)
Aciclovir
Dowelhurst Ltd
J05AB01
Aciclovir
200mg
Oral tablet
Oral
No Controlled Drug Status
Valid as a prescribable product
BNF: 05030201
Read the complete document
SUMMARY OF PRODUCT CHARACTERISTICS 1 NAME OF THE MEDICINAL PRODUCT Aciclovir 200 mg Tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION Each 200 mg tablet contains 200 mg aciclovir. For the full list of excipients, see section 6.1 3 PHARMACEUTICAL FORM Tablet White to off-white, round (diameter: 9.5 mm), biconvex, uncoated tablets debossed with ‘AR 200’ on one side and plain on the other side. 4 CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS Aciclovir Tablets are indicated for the treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes (excluding neonatal HSV and severe HSV infections in immunocompromised children). Aciclovir Tablets are indicated for the suppression (prevention of recurrences) of recurrent herpes simplex infections in immunocompetent patients. Aciclovir Tablets are indicated for the prophylaxis of herpes simplex infections in immunocompromised patients. Aciclovir Tablets are indicated for the treatment of varicella (chickenpox) and herpes zoster (shingles) infections. 4.2 POSOLOGY AND METHOD OF ADMINISTRATION Posology _ _ _Dosage in adults _ _ _ Treatment of herpes simplex infections: 200 mg Aciclovir should be taken five times daily at approximately four hourly intervals omitting the night time dose. Treatment should continue for 5 days, but in severe initial infections this may have to be extended. In severely immunocompromised patients (e.g. after marrow transplant) or in patients with impaired absorption from the gut the dose can be doubled to 400 mg Aciclovir, or alternatively, intravenous dosing could be considered. Dosing should begin as early as possible after the start of an infection; for recurrent episodes this should preferably be during the prodromal period or when lesions first appear. Suppression of herpes simplex infections in immunocompetent patients: 200 mg Aciclovir should be taken four times daily at approximately six-hourly intervals. Many patients may be conveniently managed on a regimen of 400 mg Aci Read the complete document