ACEPROMAZINE MALEATE injection

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

ACEPROMAZINE MALEATE (UNII: 37862HP2OM) (ACEPROMAZINE - UNII:54EJ303F0R)

Available from:

Covetrus North America

Administration route:

INTRAVENOUS

Prescription type:

PRESCRIPTION

Therapeutic indications:

Dogs and cats: Acepromazine maleate injection can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to control vomiting associated with motion sickness. Acepromazine maleate injection is particularly useful as a preanesthetic agent (1) to enhance and prolong the effects of barbiturates, thus reducing the requirements for general anesthesia; (2) as an adjunct to surgery under local anesthesia. Horses: Acepromazine maleate injection can be used as an aid in controlling fractious animals during examination, treatment, loading and transportation. Particularly useful when used in conjunction with local anesthesia for firing, castration, neurectomy, removal of skin tumors, ocular surgery and applying casts. Phenothiazines may potentiate the toxicity of organophosphates and the activity of procaine hydrochloride. Therefore, do not use Acepromazine maleate injection

Product summary:

Acepromazine maleate injection is supplied in 50 mL multiple dose vials. NDC 11695-0095-5 - 10 mg/mL 50 mL vial

Authorization status:

New Animal Drug Application

Summary of Product characteristics

ACEPROMAZINE MALEATE- ACEPROMAZINE MALEATE INJECTION
COVETRUS NORTH AMERICA
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ACEPROMAZINE MALEATE INJECTION
Approved by FDA under NADA # 015-030
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION:
Acepromazine maleate injection, a potent neuroleptic agent with a low
order of toxicity,
is of particular value in the tranquilization of dogs, cats and
horses. Its rapid action and
lack of hypnotic effect are added advantages. According to Baker,
the scope of
possible applications for this compound in veterinary practice is only
limited by the
imagination of the practitioner.
EACH ML CONTAINS: Acepromazine maleate 10 mg, sodium citrate 0.36%,
citric acid
0.075%, benzyl alcohol 1% and water for injection.
Acepromazine [10-[3-(dimethylamino) propyl] phenothiazin-2-yl-methyl
ketone] Maleate,
USP has the following chemical structure:
Acepromazine maleate injection has a depressant effect on the central
nervous system
and, therefore, causes sedation, muscular relaxation and a reduction
in spontaneous
activity. It acts rapidly, exerting a prompt and pronounced calming
effect.
INDICATIONS:
DOGS AND CATS: Acepromazine maleate injection can be used as an aid in
controlling
intractable animals during examination, treatment, grooming, x-ray and
minor surgical
procedures; to alleviate itching as a result of skin irritation; as an
antiemetic to control
vomiting associated with motion sickness.
Acepromazine maleate injection is particularly useful as a
preanesthetic agent (1) to
enhance and prolong the effects of barbiturates, thus reducing the
requirements for
general anesthesia; (2) as an adjunct to surgery under local
anesthesia.
HORSES: Acepromazine maleate injection can be used as an aid in
controlling fractious
animals during examination, treatment, loading and transportation.
Particularly useful
1
when used in conjunction with local anesthesia for firing, castration,
neurectomy,
removal of skin tumors, ocular surgery and applying casts.
DOSAGE AND ADMINISTRATIO