ACEPROJECT- acepromazine maleate injection

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

ACEPROMAZINE MALEATE (UNII: 37862HP2OM) (ACEPROMAZINE - UNII:54EJ303F0R)

Available from:

Henry Schein Animal Health

INN (International Name):

ACEPROMAZINE MALEATE

Composition:

ACEPROMAZINE MALEATE 10 mg in 1 mL

Administration route:

INTRAVENOUS

Prescription type:

PRESCRIPTION

Therapeutic indications:

Dogs and Cats: AceproJect can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to control vomiting associated with motion sickness. AceproJect is particularly useful as a preanesthetic agent (1) to enhance and prolong the effects of barbiturates, thus reducing the requirements for general anesthesia; (2) as an adjunct to surgery under local anesthesia. Horses: AceproJect can be used as an aid in controlling fractious animals during examination, treatment, loading and transportation. Particularly useful when used in conjunction with local anesthesia for firing, castration, neurectomy, removal of skin tumors, ocular surgery and applying casts. Phenothiazines may potentiate the toxicity of organophosphates and the activity of procaine hydrochloride. Therefore, do not use AceproJect to control tremors associated with organic phosphate poisoning. Do not use in co

Product summary:

AceproJect is supplied in 50 mL multiple dose vials. NDC 11695-0079-8 – 10 mg/mL 50 mL vial

Authorization status:

New Animal Drug Application

Summary of Product characteristics

ACEPROJECT- ACEPROMAZINE MALEATE INJECTION
HENRY SCHEIN ANIMAL HEALTH
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ACEPROJECT
(ACEPROMAZINE MALEATE INJECTION)
NADA 015-030, Approved by FDA
CAUTION:
Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DES CRIPTION:
AceproJect (acepromazine maleate injection), a potent neuroleptic
agent with a low order of toxicity, is
of particular value in the tranquilization of dogs, cats and horses.
Its rapid action and lack of hypnotic
effect are added advantages. According to Baker,
the scope of possible applications for this
compound in veterinary practice is only limited by the imagination of
the practitioner.
EACH ML CONTAINS: Acepromazine maleate 10 mg, sodium citrate 0.36%,
citric acid 0.075%, benzyl
alcohol 1% and water for injection.
Acepromazine [10-[3-(dimethylamino) propyl] phenothiazin-2-yl-methyl
ketone] Maleate, USP has the
following chemical structure:
AceproJect has a depressant effect on the central nervous system and,
therefore, causes sedation,
muscular relaxation and a reduction in spontaneous activity. It acts
rapidly, exerting a prompt and
pronounced calming effect.
INDICATIONS :
DOGS AND CATS: AceproJect can be used as an aid in controlling
intractable animals during examination,
treatment, grooming, x-ray and minor surgical procedures; to alleviate
itching as a result of skin
irritation; as an antiemetic to control vomiting associated with
motion sickness.
AceproJect is particularly useful as a preanesthetic agent (1) to
enhance and prolong the effects of
barbiturates, thus reducing the requirements for general anesthesia;
(2) as an adjunct to surgery under
local anesthesia.
HORSES: AceproJect can be used as an aid in controlling fractious
animals during examination, treatment,
loading and transportation. Particularly useful when used in
conjunction with local anesthesia for firing,
castration, neurectomy, removal of skin tumors, ocular surgery and
applying casts.
DOSAGE AND ADMINISTRATION:
The dosage should be individualized, depending upon the degree o