Accuretic 10mg/12.5mg tablets

Country: United Kingdom

Language: English

Source: MHRA (Medicines & Healthcare Products Regulatory Agency)

Active ingredient:

Hydrochlorothiazide; Quinapril hydrochloride

Available from:

Pfizer Ltd

ATC code:

C09BA06

INN (International Name):

Hydrochlorothiazide; Quinapril hydrochloride

Dosage:

12.5mg ; 10mg

Pharmaceutical form:

Oral tablet

Administration route:

Oral

Class:

No Controlled Drug Status

Prescription type:

Valid as a prescribable product

Product summary:

BNF: 02050501; GTIN: 5013457011241

Patient Information leaflet

Page 1 of 7
PACKAGE LEAFLET: INFORMATION FOR THE USER
ACCURETIC® 10/12.5 MG FILM-COATED TABLETS
quinapril and hydrochlorothiazide
READ ALL OF THIS LEAFLET CAREFULLY BEFORE YOU START TAKING THIS
MEDICINE BECAUSE IT CONTAINS IMPORTANT
INFORMATION FOR YOU.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to
others. It may harm them, even if their signs
of illness are the same as yours.
- If you get any side effects, talk to your doctor or pharmacist. This
includes any possible side effects not listed in
this leaflet. See section 4.
WHAT IS IN THIS LEAFLET
1.
What Accuretic is and what it is used for
2.
What you need to know before you take Accuretic
3.
How to take Accuretic
4.
Possible side effects
5.
How to store Accuretic
6.
Contents of the pack and other information
1.
WHAT ACCURETIC IS AND WHAT IT IS USED FOR
Accuretic contains the active substances quinapril and
hydrochlorothiazide. Quinapril belongs to a group of
medicines called angiotensin converting enzyme (ACE) inhibitors. ACE
inhibitors work by widening blood
vessels in the body, which can help to reduce the pressure in the
vessels. Hydrochlorothiazide belongs to a group
of medicines called diuretics. Diuretics help the body to get rid of
extra fluid and are used in patients with high
blood pressure. Because they get rid of fluid diuretics are sometimes
called ‘water tablets’.
Accuretic is used to treat high blood pressure.
You must talk to a doctor if you do not feel better or if you feel
worse.
2.
WHAT YOU NEED TO KNOW BEFORE YOU TAKE ACCURETIC_ _
_ _
DO NOT TAKE ACCURETIC

if you are in your second or third trimester of pregnancy. It is also
better to avoid Accuretic in early
pregnancy. See section 2 PREGNANCY, BREAST-FEEDING AND FERTILITY

if you are allergic to quinapril, hydrochlorothiazide, or any of the
other ingredients of this medicine (listed
in section 6), similar drugs or to a group of antibioti

Summary of Product characteristics

OBJECT 1
ACCURETIC FILM COATED TABLETS
Summary of Product Characteristics Updated 27-Feb-2018 | Pfizer
Limited
1. Name of the medicinal product
Accuretic 10/12.5 mg film-coated tablets.
2. Qualitative and quantitative composition
Each tablet contains 10 mg quinapril (as 10.85 mg quinapril
hydrochloride) and 12.5 mg
hydrochlorothiazide (HCTZ).
Excipient(s) with known effect:
Lactose, 30.7 mg per tablet.
For the full list of excipients, see section 6.1.
3. Pharmaceutical form
Film-coated tablet.
Pink, oval, biconvex film-coated tablets scored on both sides. The
score line is only to facilitate breaking
for ease of swallowing and not to divide into equal doses.
4. Clinical particulars
4.1 Therapeutic indications
For the treatment of all grades of essential hypertension in patients
who have been stabilised on the
individual components given in the same proportions (see sections 4.3,
4.4, 4.5 and 5.1).
4.2 Posology and method of administration
Posology
_Adults_
For patients currently not receiving a diuretic, whether or not they
have been receiving quinapril
monotherapy, the recommended initial dosage of quinapril/HCTZ is
10/12.5 mg. Following initial
therapy, the dosage may be increased to 20/25 mg. Effective blood
pressure control is usually achieved
with a dosage of 10/12.5 mg (see sections 4.3, 4.4, 4.5 and 5.1).
Take either with or without food. The dose should always be taken at
about the same time of day to help
increase compliance.
In patients with congestive heart failure, with or without associated
renal insufficiency, ACE inhibitor
therapy for hypertension may cause an excessive drop in blood
pressure. Accuretic therapy should be
started under close medical supervision. Patients should be followed
closely for the first two weeks of
treatment and whenever the dosage is increased.
_Renal Impairment_
Accuretic is not recommended for use in patients with creatinine
clearance of less than 40 mL/min.
_Elderly_
The dose should be kept as low as possible commensurate with
achievement of adequate blood pressure
cont