歐癬平凍晶注射劑

Country: Taiwan

Language: Chinese

Source: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

Active ingredient:

VORICONAZOLE

Available from:

台灣山德士藥業股份有限公司 臺北市中山區民生東路3段2號8樓 (90003886)

ATC code:

J02AC03

Pharmaceutical form:

凍晶注射劑

Composition:

VORICONAZOLE (0812204300) MG

Units in package:

小瓶;;盒裝

Class:

製　劑

Prescription type:

限由醫師使用

Manufactured by:

LEK PHARMACEUTICALS D.D., SLOVENIA VEROVSKOVA 57, SI-1526 LJUBLJANA, SLOVENIA SI

Therapeutic area:

voriconazole

Therapeutic indications:

一、治療侵犯性麴菌病（INVASIVE ASPERGILLOSIS）﹔二、治療嚴重之侵犯性念珠菌感染（SERIOUS INVASIVE CANDIDA INFECTIONS）﹔三、治療足分枝菌（SCEDOSPORIUM SPP.）和鐮刀菌（FUSARIUM SPP.）之嚴重黴菌感染﹔四、預防高危險患者發生侵入性黴菌感染，包括接受造血幹細胞移植（HSCT）的患者。

Product summary:

有效日期: 2025/12/08; 英文品名: Voriconazole Sandoz Lyophilized Powder for Injection

Authorization date:

2015-12-08

Patient Information leaflet

歐癬平凍晶注射劑
VORICONAZOLE SANDOZ
LYOPHILIZED POWDER FOR
INJECTION
歐癬平凍晶注射劑
VORICONAZOLE SANDOZ
LYOPHILIZED POWDER FOR
INJECTION
(NSAIDs)
[CYP2C9]
Ibuprofen (400)
S-Ibuprofen C
max
↑
20%
S-Ibuprofen AUC
0-
∞
↑
100%
NSAIDs
NSAIDs
Diclofenac (50)
Diclofenac C
max
↑
114%
Diclofenac AUC
0-
∞
↑
78%
Omeprazole (40QD)*
[CYP2C19CYP2C19
CYP3A4]
Omeprazole C
max
↑
116%
Omeprazole AUC
τ
↑
280%
Voriconazole C
max
↑
15%
Voriconazole AUC
τ
↑
41%
CYP2C19
voriconazole
voriconazole
40(
)
omeprazole
voriconazole
omeprazole
*
[CYP3A4CYP2C19
]
Norethisterone/ethinylestradiol
(1/0.035QD)
Ethinylestradiol C
max
↑
36%
Ethinylestradiol AUC
τ
↑
61%
Norethisterone C
max
↑
15%
Norethisterone AUC
τ
↑
53%
Voriconazole C
max
↑
14%
Voriconazole AUC
τ
↑
46%
voriconazole
[CYP3A4]
Alfentanil
(20/naloxone
)
Fentanyl (5/)
Alfentanil AUC
0-
∞
↑
6
Fentanyl AUC
0-
∞
↑
1.34
a l f e n t a n i l
f e n t a n y l
alfentanil
C Y P 3 A 4
(
sufentanil)
S t a t i n (
lovastatin)
[CYP3A4]
v o r i c o n a z o l e
CYP3A4statin
statin
S u l
p h o n y l
u r e a s (
t o l b u t a m i d e
g l i p i z i d e
glyburide)
[CYP2C9]
voriconazole
sulphonylureas
sulfonylureas
(
v i n c r i s t i n e
vinblastine)
[CYP3A4]
voriconazole
H I V (
s a q u i n a v i r
a m p r e n a v i r
nelfinavir)*
[CYP3A4]
voriconazole
HIV
voriconazole
HIV
(
)
(NNRTIs) (
delavirdine
nevirapine)*
[ C Y P 3 A 4
CYP450]
voriconazole
N N RT I s
v o r i c o n a z o l e
NNRTIs
Efavirenz
voriconazole
NNRTI
voriconazole
(
)
Cimetidine (400BID)
[CYP450
pH]
Voriconazole C
max
↑
18%
Voriconazole AUC
τ
↑
23%
Digoxin (0.25QD)
[P-gp]
D
igoxin C
max
↔
Digoxin AUC
τ
↔
Indinavir (800TID)
[CYP3A4]
Indinavir C
max
↔
Indinavir AUC
τ
↔
Voriconazole C
max
↔
Voriconazole AUC
τ
↔
Erythromycin (1BID)
[CYP3A4]
Azithromycin (500QD)
Voriconazol
e C
max
AUC
τ
↔
Voriconazol
e C
max
AUC
τ
↔
v o r i c o n a z o l e
erythromycin
azithromycin
Mycophenolic acid (1)
[UDP-]
Mycophenolic acid C
max
↔
Mycophenolic acid AUC
τ
↔
Predn