TRIHEXYPHENIDYL HYDROCHLORIDE tablet

Χώρα: Ηνωμένες Πολιτείες

Γλώσσα: Αγγλικά

Πηγή: NLM (National Library of Medicine)

Δραστική ουσία:

TRIHEXYPHENIDYL HYDROCHLORIDE (UNII: AO61G82577) (TRIHEXYPHENIDYL - UNII:6RC5V8B7PO)

Διαθέσιμο από:

NCS HealthCare of KY, Inc dba Vangard Labs

INN (Διεθνής Όνομα):

TRIHEXYPHENIDYL HYDROCHLORIDE

Σύνθεση:

TRIHEXYPHENIDYL HYDROCHLORIDE 2 mg

Οδός χορήγησης:

ORAL

Τρόπος διάθεσης:

PRESCRIPTION DRUG

Θεραπευτικές ενδείξεις:

This drug is indicated as an adjunct in the treatment of all forms of parkinsonism (post-encephalitic, arteriosclerotic, and idiopathic). It is often useful as adjuvant therapy when treating these forms of parkinsonism with levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by central nervous system drugs such as the dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.

Περίληψη προϊόντος:

Trihexyphenidyl Hydrochloride Tablets, USP 2 mg are 10/32", scored, round, white, flat faced, tablets imprinted DAN DAN and 5335 supplied in blisterpacks of 30 and 31. Trihexyphenidyl Hydrochloride Tablets USP 5 mg are 12/32", scored, round, white, tablets imprinted DAN DAN and 5337 supplied in blisterpacks of 30. Dispense in a tight container with child-resistant closure. Store at 20°-25°C (68°- 77°F). [See USP controlled room temperature.] Watson Laboratories Inc. Corona, CA 92880 USA

Καθεστώς αδειοδότησης:

Abbreviated New Drug Application

Αρχείο Π.Χ.Π.

TRIHEXYPHENIDYL HYDROCHLORIDE- TRIHEXYPHENIDYL HYDROCHLORIDE TABLET
NCS HEALTHCARE OF KY, INC DBA VANGARD LABS
----------
TRIHEXYPHENIDYL
HYDROCHLORIDE
TABLETS USP
RX ONLY
DESCRIPTION
Trihexyphenidyl hydrochloride is a synthetic antispasmodic drug
available in the following forms:
Tablets, 2 mg and 5 mg. It is designated chemically 1-Piperidinepro-
panol,α-cyclohexyl-α-phenyl-,
hydrochloride. The structural formula is represented below:
C
H NO·HCl
M.W. 337.93
Trihexyphenidyl Hydrochloride Tablets USP 2 mg and 5 mg contain the
following inactive ingredients:
colloidal silicon dioxide, dibasic calcium phosphate, lactose
monohydrate, magnesium stearate,
microcrystalline cellulose and sodium starch glycolate.
CLINICAL PHARMACOLOGY
Trihexyphenidyl HCl is the substituted piperidine salt,
3-(1-piperidyl)-1-phenyl-cyclohexyl-1-propanol
hydrochloride, which exerts a direct inhibitory effect upon the
parasympathetic nervous system. It also
has a relaxing effect on smooth musculature; exerted both directly
upon the muscle tissue itself and
indirectly through an inhibitory effect upon the parasympathetic
nervous system. Its therapeutic
properties are similar to those of atropine, although undesirable side
effects are ordinarily less
frequent and severe than with the latter.
INDICATIONS
This drug is indicated as an adjunct in the treatment of all forms of
parkinsonism (post-encephalitic,
arteriosclerotic, and idiopathic). It is often useful as adjuvant
therapy when treating these forms of
parkinsonism with levodopa. Additionally, it is indicated for the
control of extrapyramidal disorders
caused by central nervous system drugs such as the dibenzoxazepines,
phenothiazines, thioxanthenes,
and butyrophenones.
WARNINGS
Patients to be treated with trihexyphenidyl HCl should have a
gonioscope evaluation and close
20
31
monitoring of intraocular pressures at regular periodic intervals.
PRECAUTIONS
Although trihexyphenidyl HCl is _NOT_ contraindicated for patients
with cardiac, liver, or kidney
disorders, or with hypertension, suc