Suxamethonium chloride 100mg/2ml solution for injection ampoules

Χώρα: Ηνωμένο Βασίλειο

Γλώσσα: Αγγλικά

Πηγή: MHRA (Medicines & Healthcare Products Regulatory Agency)

Δραστική ουσία:

Suxamethonium chloride

Διαθέσιμο από:

Martindale Pharmaceuticals Ltd

Φαρμακολογική κατηγορία (ATC):

M03AB01

INN (Διεθνής Όνομα):

Suxamethonium chloride

Δοσολογία:

50mg/1ml

Φαρμακοτεχνική μορφή:

Solution for injection

Οδός χορήγησης:

Intravenous; Intramuscular

Kατηγορία:

No Controlled Drug Status

Τρόπος διάθεσης:

Valid as a prescribable product

Περίληψη προϊόντος:

BNF: 15010500; GTIN: 5014124170872

Φύλλο οδηγιών χρήσης

IN THIS LEAFLET:
1.
What Suxamethonium Chloride Injection
is and what it is used for
2.
Before having Suxamethonium Chloride
Injection
3.
How Suxamethonium Chloride Injection
is given
4.
Possible side effects
5.
Storing Suxamethonium Chloride
Injection
6.
Further information
1. WHAT SUXAMETHONIUM
CHLORIDE INJECTION IS AND WHAT
IT IS USED FOR
The active ingredient Suxamethonium
Chloride is a medicine that relaxes the
muscles of the body.
Suxamethonium Chloride Injection is used
to help your muscles relax during surgery
or medical procedures. It is also used to
reduce the strength of muscle contractions
associated with drug-induced convulsions
(fits) or with electro-convulsive therapy
(ECT).
2. BEFORE HAVING SUXAMETHONIUM
CHLORIDE INJECTION
YOU SHOULD NOT BE GIVEN SUXAMETHONIUM
CHLORIDE INJECTION IF:
• you are allergic to Suxamethonium
Chloride or any of the other ingredients
listed in section 6 of this leaflet
• you are pregnant, trying to become
pregnant or breast-feeding
• your doctor has told you that you suffer
from abnormal cholinesterase activity
• you or any of your family have a history of
abnormally high body temperature
(hyperthermia)
• you are recovering from major trauma or
severe burns
• you have suffered a spinal cord injury,
nerve injury or sudden muscle wasting
• you have abnormally high levels of
potassium in your blood (hyperkalaemia)
• you have any eye injuries
• you have a disease causing weakness of
the muscles (myotonia congenita,
dystrophia myotonica or myasthenia
gravis)
• you have muscle weakness and wasting
of muscle tissue (Duchenne muscular
dystrophy (DMD))
• you have not been able to walk for a
long period of time.
TAKE SPECIAL CARE WITH SUXAMETHONIUM
CHLORIDE INJECTION IF:
• you are suffering from an infection that
causes muscle stiffness (tetanus)
• you are suffering from tuberculosis
• you feel unwell
• you have a fever
• you have severe burns
• you have cancer
• you suffer from a blood disease known as
anaemia
• you suffer from a lack of proper

Αρχείο Π.Χ.Π.

OBJECT 1
SUXAMETHONIUM CHLORIDE 50MG/ML SOLUTION FOR
INJECTION
Summary of Product Characteristics Updated 10-Oct-2014 | Martindale
Pharma
1. Name of the medicinal product
Suxamethonium Chloride 50mg/ml Solution for Injection.
2. Qualitative and quantitative composition
Suxamethonium Chloride 50mg/ml (100mg/2ml).
Each ml contains 50mg of suxamethonium chloride
For excipients, see section 6.1.
3. Pharmaceutical form
Solution for Injection.
Clear, colourless solution.
4. Clinical particulars
4.1 Therapeutic indications
Used in anaesthesia as a muscle relaxant to facilitate endotracheal
intubation, mechanical ventilation and
a wide range of surgical and obstetrics procedures.
It is also used to reduce the intensity of muscular contractions
associated with pharmacologically or
electrically – induced convulsions.
4.2 Posology and method of administration
Usually by bolus injection.
_Adults and Children over 12 years_
The dose is dependent on body weight, the degree of muscular
relaxation required, the route of
administration, and the response of individual patients.
To achieve endotracheal intubation Suxamethonium Chloride is usually
administered intravenously in a
dose of 1mg/kg. This dose will usually produce muscular relaxation in
about 30 to 60 seconds and has a
duration of action of about 2 to 6 minutes. Larger doses will produce
more prolonged muscular
relaxation, but doubling the dose does not necessarily double the
duration of relaxation. Supplementary
doses of Suxamethonium Chloride of 50% to 100% of the initial dose
administered at 5 to 10 minute
intervals will maintain muscle relaxation during short surgical
procedures performed under general
anaesthesia.
For prolonged surgical procedures Suxamethonium Chloride may be given
by intravenous infusion as a
0.1% to 0.2% solution, diluted in 5% glucose solution or sterile
isotonic saline solution, at a rate of 2.5 to
4mg per minute. The infusion rate should be adjusted according to the
response of individual patients.
The total dose of Suxamethonium Chloride give