Χώρα: Καναδάς
Γλώσσα: Αγγλικά
Πηγή: Health Canada
DOCUSATE SODIUM
TEVA CANADA LIMITED
A06AA02
DOCUSATE SODIUM
20MG
SYRUP
DOCUSATE SODIUM 20MG
ORAL
25ML/500ML
OTC
CATHARTICS AND LAXATIVES
Active ingredient group (AIG) number: 0104351003; AHFS:
APPROVED
2013-06-10
PRESCRIBING INFORMATION RATIO-DOCUSATE SODIUM DOCUSATE SODIUM USP 20 MG / 5 ML SYRUP 100 MG / 25 ML SYRUP UNIDOSE STOOL SOFTENER TEVA CANADA LIMITED DATE OF PREPARATION: 30 NOVOPHARM COURT June 10, 2013 TORONTO, ONTARIO M1B 2K9, CANADA Control #: 165314 Page 2 PRESCRIBING INFORMATION RATIO-DOCUSATE SODIUM DOCUSATE SODIUM USP 20 MG / 5 ML SYRUP 100 MG / 25 ML SYRUP UNIDOSE STOOL SOFTENER ACTIONS AND CLINICAL PHARMACOLOGY RATIO-DOCUSATE SODIUM is an anionic surfactant with emulsifying, wetting and dispersing properties. In recommended oral doses, it lowers surface tension in the gastrointestinal tract, permitting water and fats to penetrate and soften fecal matter. It also appears to stimulate the secretion of water and electrolytes in the intestine. The extent to which orally administered docusate salts are absorbed has not been determined, but these drugs appear to be absorbed to some extent in the duodenum and jejunum and subsequently excreted in bile. Docusate agents do not interfere with the absorption of nutrients from gastrointestinal tract; however they increase the systemic absorption and the hepatic intake of lipids and other drugs administered concurrently, as well as increasing their toxicity. By increasing intestinal motility, RATIO-DOCUSATE SODIUM may potentially decrease transit time of concomitantly administered oral drugs and thereby decreasing their absorption. Page 3 INDICATIONS AND CLINICAL USE The management of constipation due to hard stools. In painful anorectal conditions, in cardiac and other conditions in which maximum ease of passage is desirable to avoid difficult or painful defecation and when peristaltic stimulants are contraindicated. Stool softening generally occurs within 1 to 3 days following initiation of therapy. CONTRAINDICATIONS Presence of abdominal pain, nausea, fever or vomiting. PRECAUTIONS Laxatives should not be given to children under 6 years of age unless prescribed by a physician. Since children are not usually able to describe their symptoms precisely, proper diagnosi Διαβάστε το πλήρες έγγραφο