plasma-lyte 148 and dextrose- Sodium chloride, potassium chloride, calcium chloride, sodium gluconate, sodium acetate and dextro

Χώρα: Ηνωμένες Πολιτείες

Γλώσσα: Αγγλικά

Πηγή: NLM (National Library of Medicine)

Δραστική ουσία:

Dextrose hydrous (UNII: LX22YL083G) (dextrose - UNII:IY9XDZ35W2), Sodium Chloride (UNII: 451W47IQ8X) (Sodium Chloride - UNII:451W47IQ8X), Potassium Chloride (UNII: 660YQ98I10) (Potassium Chloride - UNII:660YQ98I10), Magnesium Chloride (UNII: 02F3473H9O) (Magnesium Chloride - UNII:02F3473H9O), Sodium Gluconate (UNII: R6Q3791S76) (sodium gluconate - UNII:R6Q3791S76), Sodium Acetate (UNII: 4550K0SC9B) (sodium acetate - UNII:4550K0SC9B)

Διαθέσιμο από:

Baxter Healthcare Corporation

INN (Διεθνής Όνομα):

Sodium chloride, potassium chloride, calcium chloride, sodium gluconate, sodium acetate and dextrose

Φαρμακοτεχνική μορφή:

INJECTION, SOLUTION

Σύνθεση:

5 g in 100 mL

Οδός χορήγησης:

INTRAVENOUS

Τρόπος διάθεσης:

PRESCRIPTION DRUG

Θεραπευτικές ενδείξεις:

Plasma-Lyte® 148 and 5% Dextrose Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) is indicated as a source of water, electrolytes, and calories, or as an alkalinizing agent. Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.

Περίληψη προϊόντος:

Plasma-Lyte® 148 and 5% Dextrose Injection (Multiple Electrolytes and Dextrose Injection, Type 1, USP) in Viaflex® plastic containers is available as shown below: Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C); brief exposure up to 40°C does not adversely affect the product.

Αρχείο Π.Χ.Π.

PLASMA-LYTE 148 AND DEXTROSE- SODIUM CHLORIDE, POTASSIUM CHLORIDE,
CALCIUM CHLORIDE,
SODIUM GLUCONATE, SODIUM ACETATE AND DEXTROSE INJECTION, SOLUTION
BAXTER HEALTHCARE CORPORATION
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PLASMA-LYTE® 148 AND 5% DEXTROSE INJECTION
(MULTIPLE ELECTROLYTES AND DEXTROSE INJECTION, TYPE 1, USP)
IN VIAFLEX® PLASTIC CONTAINER
DESCRIPTION
Plasma-Lyte® 148 and 5% Dextrose Injection (Multiple Electrolytes and
Dextrose Injection, Type 1,
USP) is a sterile, nonpyrogenic solution for fluid and electrolyte
replenishment and caloric supply in a
single dose container for intravenous administration. Each 100 mL
contains 5 g Dextrose Hydrous,
USP*, 526 mg Sodium Chloride, USP (NaCl); 502 mg Sodium Gluconate (C H
NaO ); 368 mg Sodium
Acetate Trihydrate, USP (C H NaO •3H O), 37 mg Potassium Chloride,
USP (KCl); and 30 mg
Magnesium Chloride, USP (MgCl
•6H O). It contains no antimicrobial agents. The pH is 5.0 (4.0 to
6.5). The pH is adjusted with hydrochloric acid.
Plasma-Lyte® 148 and 5% Dextrose Injection (Multiple Electrolytes and
Dextrose Injection, Type 1,
USP) administered intravenously has value as a source of water,
electrolytes, and calories. One liter has
an ionic concentration of 140 mEq sodium, 5 mEq potassium, 3 mEq
magnesium, 98 mEq chloride, 27
mEq acetate and 23 mEq gluconate. The osmolarity is 547 mOsmol/L
(calc). Normal physiologic
osmolarity range is approximately 280 to 310 mOsmol/L. Administration
of substantially hypertonic
solutions (≥ 600 mOsmol/L) may cause vein damage. The caloric
content is 190 kcal/L.
The Viaflex® plastic container is fabricated from a specially
formulated polyvinyl chloride (PL 146®
Plastic). The amount of water that can permeate from inside the
container into the overwrap is
insufficient to affect the solution significantly. Solutions in
contact with the plastic container may leach
out certain chemical components from the plastic in very small
amounts; however, biological testing
was supportive of the safety of the plastic container materials.
CLINICAL PHARMACOLOGY
Plasma