Χώρα: Μαλαισία
Γλώσσα: Αγγλικά
Πηγή: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Omeprazole Pellets 8.5%
MILRIN PHARMACEUTICAL CO. (M) SDN BHD
Omeprazole Pellets 8.5%
14Capsule Capsules
The United Drug (1996) Co., Ltd.
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ MILOSEC ® CAPSULE Omeprazole (20mg) 1 WHAT IS IN THIS LEAFLET 1. What MILOSEC ® is used for 2. How MILOSEC ® works 3. Before you use MILOSEC ® 4. How to use MILOSEC ® 5. While you are using MILOSEC ® 6. Side effects 7. Storage and disposal of MILOSEC ® 8. Product description 9. Manufacturer and Product Registration Holder 10. Date of Revision WHAT MILOSEC ® IS USED FOR MILOSEC ® is used to reduce the amount of acid in your stomachs such as gastric, duodenal ulcers, or gastroesophageal reflux disease or Zollinger-Ellison syndrome. This medicine can also be used to treat stomach infections caused by _Helicobacter pylori_ bacteria. HOW MILOSEC ® WORKS MILOSEC ® contains Omeprazole which works by reducing gastric acid secretion. BEFORE YOU USE MILOSEC ® - _When you must not use it _ Do NOT take MILOSEC ® if you are allergic (hypersensitive) to omeprazole or any of the other ingredients. - _Before you start to use it_ Tell your doctor if you are - having liver problems - due to having a specific blood test (Chromogranin A) - _Taking other medicines_ Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription especially: - diazepam (use to treat anxiety) - warfarin (use to treat blood clots) - phenytoin (use to prevent and control seizure) PREGNANCY AND BREASTFEEDING It is preferable not to take this product during pregnancy. If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking MILOSEC ® . You should not breastfeed while taking this medicine. If you are breastfeeding or planning to breastfeed, talk to your doctor before taking this medicine. HOW TO USE MILOSEC ® - _How much to use_ Follow the directions given to you by your doctor and pharmacist carefully. These directions may differ from the information contained in this leaflet. DUODENAL ULCER TREATMENT OR PREVENTION: Recommended Dosage: MILOSEC ® 20 Διαβάστε το πλήρες έγγραφο
MILOSEC ® Capsule 20 mg ( Omeprazole 20 mg) Composition: Each capsule contains Omeprazole Pellets equivalent to Omeprazole 20 mg Product Description: Opaque pink-reddish brown capsule No.2, imprinted “Frx Frx” in black color, containing off-white enteric coated pellet. Pharmacodynamics: Omeprazole reduces gastric acid secretion through a highly selective mechanism of action. It produces specific dose- dependent inhibition of the enzyme H + , K + -ATPase (the proton pump) in the parietal cell. As this action inhibits the final stage of gastric acid formation, there is an effective inhibition of both basal and stimulated acid secretion irrespective of the stimulus to acid formation. Omeprazole has no effect on acetylcholine or histamine receptors and no clinically significant pharmacodynamic effects have been observed other than those explained by the effect of omeprazole on acid secretion. The onset of action is rapid and reversible control of gastric secretion is achieved with once-daily dosing. During treatment with antisecretory medicinal products, serum gastrin increase in response to the decreased acid secretion. Also CgA increases due to decreased gastric acidity. The increased CgA level may interfere with investigations for neuroendocrine tumors. Available published evidence suggested that proton pump inhibitors should be discontinued between 5 days and 2 weeks prior to CgA measurements. This is to allow CgA levels that might be spuriously elevated following PPI treatment to return to reference range. Pharmacokinetics: Omeprazole is rapidly but variably absorbed after oral doses. Absorption is not affected by food. Omeprazole is acid-labile and pharmacokinetics may vary between the various formulations developed to improve oral bioavailability. The absorption of omeprazole also appears to be dose-dependent; increasing the dosage above 40 mg has been reported to increase the plasma concentrations in a non-linear fashion because of saturable first-pass hepatic-metabolism. In addition, absorption is highe Διαβάστε το πλήρες έγγραφο