Hovid Desolvon-30 Tablet

Χώρα: Μαλαισία

Γλώσσα: Αγγλικά

Πηγή: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Δραστική ουσία:

Ambroxol Hydrochloride

Διαθέσιμο από:

HOVID BERHAD

INN (Διεθνής Όνομα):

Ambroxol Hydrochloride

Μονάδες σε πακέτο:

10 Tablet Tablets; 100 Tablets

Κατασκευάζεται από:

HOVID BERHAD

Φύλλο οδηγιών χρήσης

NOT APPLICABLE

Αρχείο Π.Χ.Π.

565
DESOLVON-30 TABLET
VIDES03-var
DESCRIPTION
White, round, flat bevel edge, and uncoated tablets with break
line on one side and plain on other side.
COMPOSITION
Ambroxol hydrochloride 30 mg.
ACTIONS AND PHARMACOLOGY
Ambroxol is a metabolite of bromhexine and is used similarly
as a mucolytic. Preclinically, ambroxol has been shown to
increase respiratory tract secretion. It enhances pulmonary
surfactant production and stimulates ciliary activity. These
actions
result
in
improved
mucus
flow
and
transport
(mucociliary clearance). Improvement of mucociliary clearance
has
been
shown
in
clinical
pharmacologic
studies.
Enhancement of fluid secretion and mucociliary clearance
facilitates expectoration and eases cough.
PHARMACOKINETICS
Ambroxol hydrochloride is completely absorbed after oral
administration. It reaches maximum plasma concentration 9 to
10 hours. Time to peak concentration after oral administration
is approximately two hours. After oral administration, 85% of
the active substance is eliminated in the urine.
INDICATIONS
Secretolytic treatment for acute & chronic bronchopulmonary
disease associated with abnormal mucus secretion & impaired
mucus transport.
CONTRAINDICATIONS
Hypersensitivity
to
ambroxol
or
other
components
of
the
formulation.
WARNINGS AND PRECAUTIONS
•
Medical advice should be sought for patients with liver and
kidney problems before taking this medication.
•
Special care is recommended during the first three months
of pregnancy. Risk-benefits should be considered against
possible effects on the child.
•
Do not use ambroxol hydrochloride if allergic to ambroxol or
to any of the other ingredients in Desolvon. Consult doctor
or pharmacist of any allergies.
•
Ambroxol may increase the amount of antibiotic penetration.
•
Be aware that all the medicines carry some risks and that all
possible risks may not be known at this stage despite
thorough testing.
•
Medical advice should be sought if the symptoms last longer
than 14 days and/or if the symptoms increase in spite of the
treatment.