Χώρα: Ηνωμένες Πολιτείες
Γλώσσα: Αγγλικά
Πηγή: NLM (National Library of Medicine)
EPINEPHRINE (UNII: YKH834O4BH) (EPINEPHRINE - UNII:YKH834O4BH)
Hospira, Inc.
EPINEPHRINE
EPINEPHRINE 0.1 mg in 1 mL
INTRAVENOUS
PRESCRIPTION DRUG
Epinephrine Injection, USP is indicated for intravenous injection in (1) treatment of acute hypersensitivity (anaphylactoid reactions to drugs, animal serums and other allergens), (2) treatment of acute asthmatic attacks to relieve bronchospasm not controlled by inhalation or subcutaneous administration of other solutions of the drug and (3) treatment and prophylaxis of cardiac arrest and attacks of transitory atrioventricular (A-V) heart block with syncopal seizures (Stokes-Adams Syndrome). In acute attacks of ventricular standstill, physical measures should be applied first. When external cardiac compression and attempts to restore the circulation by electrical defibrillation or use of a pacemaker fail, intracardiac puncture and intramyocardial injection of epinephrine may be effective. Epinephrine is contraindicated in patients with known hypersensitivity to sympathomimetic amines, in patients with angle closure glaucoma, and patients in shock (nonanaphylactic). It should not be used in patients anesthetiz
Epinephrine Injection, USP is supplied in single-dose containers as follows: Unit of Sale Total Strength/ Total Volume (Concentration) Each NDC 0409-4901-18 Bundle of 10 1 mg/10 mL (0.1 mg/mL) NDC 0409-4901-10 10 mL Single-dose Abboject™ Glass Syringe (18 G x 3 1/2 inch) NDC 0409-4921-34 Bundle of 10 1 mg/10 mL (0.1 mg/mL) NDC 0409-4921-20 10 mL Single-dose Lifeshield™ Abboject™ Glass Syringe* (20 G x 1 1/2 inch) Store at 20 to 25ºC (68 to 77ºF). [See USP Controlled Room Temperature.] Protect from light. TO PREVENT NEEDLE-STICK INJURIES, NEEDLES SHOULD NOT BE RECAPPED, PURPOSELY BENT OR BROKEN BY HAND. Hospira, Inc., Lake Forest, IL 60045 USA Abboject™ is a trademark of Abbott Laboratories. LAB-1136-1.0 Revised: 09/2017
unapproved drug other
EPINEPHRINE- EPINEPHRINE INJECTION, SOLUTION HOSPIRA, INC. _Disclaimer: This drug has not been found by FDA to be safe and effective, and this_ _labeling has not been approved by FDA. For further information about unapproved_ _drugs, click here._ ---------- EPINEPHRINE INJECTION, USP 1 MG/10 ML (0.1 MG/ML) ABBOJECT™ SYRINGE FLIPTOP VIAL PROTECT SOLUTION FROM LIGHT; DO NOT USE THE INJECTION IF ITS COLOR IS PINKISH OR DARKER THAN SLIGHTLY YELLOW OR IF IT CONTAINS A PRECIPITATE. Rx only _DESCRIPTION_ Epinephrine Injection, USP is a sterile, nonpyrogenic solution administered parenterally by the intravenous or intracardiac (left ventricular chamber) routes, or via endotracheal tube into the bronchial tree. Each milliliter (mL) contains epinephrine 0.1 mg; sodium chloride 8.16 mg; sodium metabisulfite added 0.46 mg; citric acid, anhydrous 2 mg and sodium citrate, dihydrate 0.6 mg added as buffers. May contain additional citric acid and/or sodium citrate for pH adjustment. pH 3.3 (2.2 to 5.0). Epinephrine Injection, USP is oxygen sensitive. The solution contains no bacteriostat or antimicrobial agent and is intended for use only as a single-dose injection. When smaller doses are required the unused portion should be discarded. Epinephrine Injection, USP is a parenteral adrenergic (sympathomimetic) agent and cardiac stimulant. The drug belongs to the group of endogenous compounds known as catecholamines. Sodium Chloride, USP is chemically designated NaCl, a white crystalline powder freely soluble in water. Epinephrine, USP is chemically designated 4-[1-hydroxy-2-(methylamino) ethyl]-1, 2 benzenediol, a white, microcrystalline powder. With acids, it forms salts that are freely soluble in water. Epinephrine has the following structural formula: _CLINICAL PHARMACOLOGY_ The actions of epinephrine resemble the effects of stimulation of adrenergic nerves. To a variable degree it acts on both alpha and beta receptor sites of sympathetic effector cells. Its most prominent actions are on the beta receptors of the heart, vascul Διαβάστε το πλήρες έγγραφο