Χώρα: Αυστραλία
Γλώσσα: Αγγλικά
Πηγή: Department of Health (Therapeutic Goods Administration)
cefazolin sodium, Quantity: 2096 mg (Equivalent: cefazolin, Qty 2000 mg)
Sandoz Pty Ltd
Injection, powder for
Excipient Ingredients:
Oral
1 infusion bottle, 10 infusion bottles, 5 infusion bottles
(S4) Prescription Only Medicine
Treatment of the following serious infections due to susceptible organisms: Respiratory tract infections due to Strep. pneumoniae, Klebsiella sp., H. influenzae, Staph. aureus (penicillin sensitive and penicillin resistant) and group A beta-haemolytic streptococci. Injectable benzathine penicillin is considered to be the drug of choice in the treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever. Cephazolin is effective in the eradication of streptococci from the nasopharynx; however, data establishing the efficacy of cephazolin in the subsequent prevention of rheumatic fever are not available at present. Genitourinary tract infections due to E. coli, P. mirabilis, and klebsiella sp. and some strains of enterobacter and enterococci. Skin and skin structure infections due to Staph. aureus (penicillin sensitive and penicillin resisant) and group A beta-haemolytic streptococci and other strains of streptococci. Bone and joint infections due to Staph. aureus. Septicaemia due to Strep. pneumoniae, Staph. aureus (penicillin sensitive and penicillin resistant), E. coli, P. mirabilis, and klebsiella sp. Endocarditis due to staph. aureus (penicillin sensitive and penicillin resistant) and group A beta-haemolytic streptococci. NOTE: Appropriate culture and susceptibility studies should be preformed to determine susceptibility of the causative organism to cephazolin.
Visual Identification: Clear glass infusion bottle containing a white to slightly yellowish powder.; Container Type: Bottle; Container Material: Glass Type II Clear; Container Life Time: 3 Years; Container Temperature: Store below 25 degrees Celsius
Registered
2004-05-05
CEFAZOLIN SANDOZ ® _Cephazolin sodium powder for injection_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Cefazolin Sandoz. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you using Cefazolin Sandoz against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT USING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT CEFAZOLIN SANDOZ IS USED FOR The name of your medicine is Cefazolin Sandoz. It contains the active ingredient cephazolin sodium. Cefazolin Sandoz is an antibiotic used to treat infections in different parts of the body caused by bacteria. Cefazolin Sandoz belongs to a group of antibiotics called cephalosporins. These antibiotics work by killing the bacteria that are causing your infection. Your doctor may have prescribed Cefazolin Sandoz for another reason. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY CEFAZOLIN SANDOZ HAS BEEN PRESCRIBED FOR YOU. Cefazolin Sandoz is available only with a doctor's prescription. It is not addictive. BEFORE YOU ARE GIVEN CEFAZOLIN SANDOZ _WHEN YOU MUST NOT BE GIVEN_ _CEFAZOLIN SANDOZ_ DO NOT USE CEFAZOLIN SANDOZ IF: 1. YOU HAVE AN ALLERGY TO THE ACTIVE INGREDIENT, CEPHAZOLIN SODIUM, OR TO ANY OTHER CEPHALOSPORINS Some of the symptoms of an allergic reaction may include asthma, wheezing, shortness of breath, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, skin rash, itching or hives. 2. YOU HAVE HAD A SERIOUS ALLERGIC REACTION TO ANY PENICILLINS. You may be more likely to have an allergic reaction to Cefazolin Sandoz if you are allergic to penicillin medicines. DO NOT USE CEFAZOLIN SANDOZ IF THE PACKAGING IS TORN OR SHOWS SIGNS OF TAMPERING. DO NOT USE CEFAZOLIN SANDOZ AFTER THE EXPIRY DATE ON THE PACK HAS PASSED. IF YOU ARE NOT S Διαβάστε το πλήρες έγγραφο
_Product Information (Registered Version) _ _ _ _Page 1 _ _Cefazolin Sandoz 1g & 2g powder for injection _ _03/2012 _ _Sandoz Pty Ltd _ _ _ _Version 05 _ _ _ _ _ _ _ _ _ _ _ _CEFAZOLIN SANDOZ_ _®_ _ _ NAME OF THE MEDICINE _Active_: Cephazolin sodium; sodium content is 48.3mg/g of cephazolin sodium _Chemical structure of cephazolin sodium _ _Chemical name_: (_6R,7R_)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl]-8-oxo-7-[2-(1_H_-tetrazol-1-yl) acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. _Molecular formula: _ C 14 H 13 N 8 NaO 4 S 3 _Molecular weight: _ 476.5 _CAS: _ _ _ _ _ 27164-46-1_ _ _ _ DESCRIPTION Cephazolin sodium is a white to off-white crystalline powder with a solubility in water of greater than or equal to 100mg/mL. Cefazolin Sandoz powder for injection contains cephazolin sodium as a single ingredient. PHARMACOLOGY _PHARMACODYNAMICS _ Semi-synthetic cephalosporin for parenteral administration. Microbiology _In vitro_ tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. Cephazolin is active against the following organisms _in _ _vitro_: _Staphylococcus aureus_ (penicillin sensitive and penicillin resistant); group A beta-haemolytic streptococci and other strains of streptococci (many strains of enterococci are resistant); _Streptococcus pneumoniae_, _ Escherichia coli_, _ Proteus mirabilis,_ Klebsiella sp., _ Enterobacter _ _aerogenes_, _Haemophilus influenzae_. Most strains of _Enterobacter cloacae_ and indole-positive proteus (_P. vulgaris, P. morganii, P. rettgeri_) are resistant. Methicillin resistant staphylococci, serratia, pseudomonas, _ Acinetobacter calcoaceticus_ (formerly Mima and Herellea sp.) are almost uniformly resistant to cephazolin. _Susceptibility tests _ Dilution or diffusion techniques – either quantitative (MIC) or breakpoint, should be used following a regularly updated, recognised and standardised method (e.g. NCCLS). Standardised susceptibility test procedures require the use of laboratory control Διαβάστε το πλήρες έγγραφο