Χώρα: Ηνωμένες Πολιτείες
Γλώσσα: Αγγλικά
Πηγή: NLM (National Library of Medicine)
FLURALANER (UNII: WSH8393RM5) (FLURALANER - UNII:WSH8393RM5), MOXIDECTIN (UNII: NGU5H31YO9) (MOXIDECTIN - UNII:NGU5H31YO9)
Merck Sharp & Dohme Corp.
TOPICAL
PRESCRIPTION
Bravecto Plus is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment of infections with intestinal roundworm (Toxocara cati ; 4th stage larvae, immature adults and adults) and hookworm (Ancylostoma tubaeforme ; 4th stage larvae, immature adults and adults). Bravecto Plus kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis ) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick) and Haemaphysalis longicornis (Asian longhorned tick)] for 2 months in cats and kittens 6 months of age and older and weighing 2.6 lb or greater. There are no known contraindications for the use of the product.
Bravecto Plus is available in three tube sizes to treat cats ranging in weight from 2.6 lb – 27.5 lb (1.2 kg to 12.5 kg). Each tube is packaged individually in a pouch. Product may be supplied in 1 or 2 tubes per carton.
New Animal Drug Application
BRAVECTO PLUS- FLURALANER AND MOXIDECTIN SOLUTION MERCK SHARP & DOHME CORP. ---------- BRAVECTO PLUS (FLURALANER AND MOXIDECTIN TOPICAL SOLUTION) FOR CATS CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: Each tube is formulated to provide a minimum dose of 18.2 mg/lb (40 mg/kg) fluralaner and 0.9 mg/lb (2 mg/kg) moxidectin. Each milliliter contains 280 mg of fluralaner and 14 mg of moxidectin. The chemical name of fluralaner is (±)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)- 4,5- dihydroisoxazol-3-yl]-2-methyl-_N_-[2-oxo-2-(2,2,2- trifluoroethylamino)ethyl]benzamide. The chemical name of moxidection is (2aE,4E,5'R,6R,6'S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(E)-1,3-Dimethyl-1- butenyl]-5',6,6',7,10,11,14,15,17a,20,20a,20b-dodecahydro-20,20b-dihydroxy- 5',6,8,19-tetramethylspiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6] benzodioxacyclooctadecin-13,2'-[2H]pyran]-4',17(3'H)-dione 4'-(E)-(O-methyloxime). Inactive ingredients: dimethylacetamide, glycofurol, diethyltoluamide, acetone, butylhydroxytoluene INDICATIONS: Bravecto Plus is indicated for the prevention of heartworm disease caused by _Dirofilaria_ _immitis_ and for the treatment of infections with intestinal roundworm (_Toxocara cati_; 4 stage larvae, immature adults and adults) and hookworm (_Ancylostoma tubaeforme_; 4 stage larvae, immature adults and adults). Bravecto Plus kills adult fleas and is indicated for the treatment and prevention of flea infestations (_Ctenocephalides felis_) and the treatment and control of tick infestations [_Ixodes scapularis_ (black-legged tick), _Dermacentor variabilis_ (American dog tick) and _Haemaphysalis longicornis_ (Asian longhorned tick)] for 2 months in cats and kittens 6 months of age and older and weighing 2.6 lb or greater. DOSAGE AND ADMINISTRATION: Bravecto Plus should be administered topically as a single dose every 2 months according to the DOSAGE SCHEDULE below to provide a minimum dose of 18.2 mg/lb (40 mg/kg) fluralaner and 0.9 mg/lb ( Διαβάστε το πλήρες έγγραφο